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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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248 RNA-SM complexes found
Structure of complex 7fhi

7fhi

Interaction between a fluoroquinolone derivative and RNAs with a single bulge

SM: 53D

Structure of complex 7fj0

7fj0

Interaction between a fluoroquinolone derivative and RNAs with a single bulge

SM: 53D

Structure of complex 7jyy

7jyy

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA)pUpUpApApA (Cap-0) and S-Adenosylmethionine (SAM).

SM: SAM SAM

Structure of complex 7jz0

7jz0

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1) and S-Adenosyl-L-homocysteine (SAH).

SM: SAH SAH

Structure of complex 7k9d

7k9d

Crystal structure of Bacillus halodurans OapB in complex with its OLE RNA target (crystal form I)

SM: EPE

Structure of complex 7kkv

7kkv

Crystal structure of Bacillus halodurans OapB in complex with its OLE RNA target (native, crystal form I)

SM: EPE

Structure of complex 7mjv

7mjv

MiaB in the complex with s-adenosylmethionine and RNA

SM: SAM

Structure of complex 7mjw

7mjw

Methylated MiaB in the complex with 5'-deoxyadenosine, methionine and RNA

SM: 5AD 5AD ZKP ZKP

Structure of complex 7mjx

7mjx

MiaB in the complex with 5'-deoxyadenosine, methionine and RNA

SM: 5AD 5AD

Structure of complex 7mkn

7mkn

Escherichia coli RNA polymerase and RapA elongation complex

SM: 2TM

Structure of complex 7mko

7mko

Escherichia coli RNA polymerase elongation complex

SM: 2TM

Structure of complex 7n2m

7n2m

Crystal structure of DNA polymerase alpha catalytic core in complex with dCTP and template/primer having T-C mismatch at the post-insertion site

SM: DCP

Structure of complex 7ojn

7ojn

Lassa virus L protein in an elongation conformation [ELONGATION]

SM: 2KH

Structure of complex 7orj

7orj

La Crosse virus polymerase at transcription capped RNA cleavage stage

SM: ATP

Structure of complex 7ork

7ork

La Crosse virus polymerase in transcription mode with cleaved capped RNA entering the polymerase active site

SM: ATP

Structure of complex 7orn

7orn

La Crosse virus polymerase at replication initiation stage

SM: ATP

Structure of complex 7po6

7po6

Xist (m6A)UCG tetraloop RNA bound to the YTH domain of YTHDC1

SM: GTP

Structure of complex 7vba

7vba

Structure of the pre state human RNA Polymerase I Elongation Complex

SM: 2TM

Structure of complex 7xpl

7xpl

Crystal structure of a C/D-free RNA-guided RNA 2'-O-methyltransferase

SM: SAH SAH

Structure of complex 7yed

7yed

In situ structure of polymerase complex of mammalian reovirus in the elongation state

SM: UTP

Structure of complex 8as7

8as7

Structure of the SFTSV L protein stalled at early elongation [EARLY-ELONGATION]

SM: 2KH EPE

Structure of complex 8asb

8asb

Structure of the SFTSV L protein stalled at early elongation with the endonuclease domain in a raised conformation [EARLY-ELONGATION-ENDO]

SM: 2KH

Structure of complex 8asd

8asd

Structure of the SFTSV L protein stalled at late elongation [LATE-ELONGATION]

SM: 2KH

Structure of complex 8ej3

8ej3

M. tuberculosis RNAP pause escaped complex with Bacillus subtilis NusG and GMPCPP

SM: G2P

Structure of complex 8g4w

8g4w

Cryo-EM consensus structure of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase plus preQ1 ligand

SM: PRF

Structure of complex 8g7e

8g7e

Cryo-EM structure of 3DVA component 0 of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase plus preQ1 ligand

SM: PRF

Structure of complex 8g8z

8g8z

Cryo-EM structure of 3DVA component 1 of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase plus preQ1 ligand

SM: PRF

Structure of complex 8gh6

8gh6

Bombyx mori R2 retrotransposon initiating target-primed reverse transcription

SM: TTP

Structure of complex 8gs2

8gs2

Structure of the Cas7-11-Csx29-guide RNA-target RNA (non-matching PFS) complex

SM: C5P

Structure of complex 8gwe

8gwe

SARS-CoV-2 E-RTC complex with RNA-nsp9 and GMPPNP

SM: GNP

Structure of complex 8h0s

8h0s

Crystal structure of MnmM from B. subtilis complexed with Gln-TTG anti-codon stem loop and SAM (2.90 A)

SM: SAM SAM

Structure of complex 8i43

8i43

Interaction between a fluoroquinolone derivative KG022 and RNAs: effect of base pairs 3' adjacent to the bulge out residues

SM: 53D

Structure of complex 8i44

8i44

Interaction between a fluoroquinolone derivative KG022 and RNAs: effect of base pairs 3' adjacent to the bulge out residues

SM: 53D

Structure of complex 8i45

8i45

Interaction between a fluoroquinolone derivative KG022 and RNAs: effect of base pairs 3' adjacent to the bulge out residues

SM: 53D

Structure of complex 8i46

8i46

Interaction between a fluoroquinolone derivative KG022 and RNAs: effect of base pairs 3' adjacent to the bulge out residues

SM: 53D

Structure of complex 8jy0

8jy0

Crystal structure of RhoBAST complexed with TMR-DN

SM: V8C V8C V8C

Structure of complex 8opp

8opp

Structure of human terminal uridylyltransferase 7 (hTUT7/ZCCHC6) bound with pre-let7g miRNA and UTPalphaS

SM: P5E

Structure of complex 8pnq

8pnq

Influenza A/H7N9 polymerase in elongation state with continuous Pol II pS5 CTD peptide mimic bound in site 1A/2A

SM: 2KH

Structure of complex 8psx

8psx

Tilapia Lake Virus polymerase in vRNA elongation state (transcriptase conformation)

SM: A0I

Structure of complex 8psz

8psz

Tilapia Lake Virus polymerase in vRNA elongation state with additional mode B promoter (transcriptase conformation)

SM: A0I

Structure of complex 8qmh

8qmh

Crystal structure of RNA G2C4 repeats in complex with small synthetic molecule ANP77

SM: W53

Structure of complex 8qz8

8qz8

Tilapia Lake Virus polymerase in vRNA pre-termination state (transcriptase conformation)

SM: G2P

Structure of complex 8r62

8r62

Solution structure of Risdiplam bound to the RNA duplex formed upon 5'-splice site recognition

SM: Y59

Structure of complex 8r63

8r63

Solution structure of branaplam bound to the RNA duplex formed upon 5'-splice site recognition

SM: Y53

Structure of complex 8r6y

8r6y

Structure of the SFTSV L protein stalled in a transcription-specific early elongation state with bound capped RNA [TRANSCRIPTION-EARLY-ELONGATION]

SM: 2KH

Structure of complex 8r8p

8r8p

Solution structure of SMN-CX bound to the RNA helix formed upon SMN2 exon7 5'-splice site recognition

SM: YB3

Structure of complex 8sq9

8sq9

SARS-CoV-2 replication-transcription complex bound to nsp9 and UMPCPP, as a pre-catalytic NMPylation intermediate

SM: WSB

Structure of complex 8sqj

8sqj

SARS-CoV-2 replication-transcription complex bound to RNA-nsp9, as a noncatalytic RNA-nsp9 binding mode

SM: VSN

Structure of complex 8ub7

8ub7

Diversity-generating retroelement (DGR) ribonucleoprotein reverse transcriptase - Active state (N-occupied)

SM: DCP

Structure of complex 8vuo

8vuo

Crystal structure of SARS-CoV-2 nsp16/nsp10 in complex with Cap-1 RNA

SM: SAH SAH

Structure of complex 8z8x

8z8x

Cryo-EM structure of Thogoto virus polymerase in a transcription initiation conformation

SM: G2P

Structure of complex 8z90

8z90

Cryo-EM structure of Thogoto virus polymerase in transcription initiation conformation 2

SM: G2P

Structure of complex 8znq

8znq

Solution structure of the complex of naphthyridine-azaquinolone and an RNA with ACG/AUA motif

SM: NAZ

Structure of complex 9avr

9avr

Human eIF4A-1 in complex with AMP-PNP, RNA, and the inhibitor silvestrol

SM: A1AG8

Structure of complex 9c0j

9c0j

Structure of the elongating DRT2 reverse transcriptase in complex with its non-coding RNA and dNTPs

SM: TTP

Structure of complex 9cpd

9cpd

Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1

SM: MQC

Structure of complex 9cpg

9cpg

Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1

SM: A1AZM

Structure of complex 9cpi

9cpi

Structures of small molecules bound to RNA repeat expansions that cause Huntington's disease-like 2 and myotonic dystrophy type 1

SM: A1AZL

Structure of complex 9did

9did

Rous sarcoma virus frameshifting pseudoknot RNA

SM: TAM

Structure of complex 9dll

9dll

NMR structures of small molecules bound to a model of an RNA CAG repeat expansion.

SM: A1AZM