Complex 7po6
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 1.77 |
| System mass | 72.16 kDa |
| Deposition year | 2021 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 7po6 |
| Reference | Jones Alisha N, Tikhaia Ekaterina, Mourão André, Sattler Michael. 2022. Structural effects of m6A modification of the Xist A-repeat AUCG tetraloop and its recognition by YTHDC1 Nucleic Acids Research |
| Equivalence Class |
NR_all_11347.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | GTP |
| Residue | . / 101 |
| Chain | G / D |
| Non-redundant | True |
| Interacting RNA chains | A/D |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | A/D: unknown |
| RNA family global | unknown |
| Volume | 50.08 Å3 |
| Hydrophobicity | 0.034 |
| Hydrophilicity | 0.515 |
| Buriedness | 0.313 |
| Don/acc character | 1.458 |
| SiteScore | 0.688 |
| D Score | 0.760 |
| Kd | — |