HARIBOSS logo

HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 7mkn

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 3.30
System mass 495.95 kDa
Deposition year 2021
Molecule type RNA/DNA/Protein
# RNA entities 1
Organism Escherichia
RCSB PDB Entry 7mkn
Reference Qayyum M. Zuhaib, Molodtsov Vadim, Renda Andrew, Murakami Katsuhiko S.. 2021. Structural basis of RNA polymerase recycling by the Swi2/Snf2 family of ATPase RapA in Escherichia coli Journal of Biological Chemistry

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound 2TM
Residue . / 101
Chain M / T
Non-redundant True
Interacting RNA chains H/R
RNA environment detailled DNA, protein, ion
RNA environment global RNA/DNA/Protein
RNA family chains H/R: unknown
RNA family global unknown
Volume 771.06 Å3
Hydrophobicity 0.227
Hydrophilicity 1.029
Buriedness 0.779
Don/acc character 1.143
SiteScore 1.057
D Score 1.072
Kd