Complex 8a5i
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.30 |
| System mass | 1341.56 kDa |
| Deposition year | 2022 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Listeria |
| RCSB PDB Entry | 8a5i |
| Reference | Koller Timm O, Turnbull Kathryn J, Vaitkevicius Karolis, Crowe-McAuliffe Caillan, Roghanian Mohammad, Bulvas Ondřej, Nakamoto Jose A, Kurata Tatsuaki, Julius Christina, Atkinson Gemma C, Johansson Jörgen, Hauryliuk Vasili, Wilson Daniel N. 2022. Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes Nucleic Acids Research |
| Equivalence Class |
NR_all_41466.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | 3QB |
| Residue | . / 3156 |
| Chain | EG / A |
| Non-redundant | True |
| Interacting RNA chains | J/A |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | J/A: rRNA |
| RNA family global | rRNA |
| Volume | 699.03 Å3 |
| Hydrophobicity | 0.420 |
| Hydrophilicity | 1.169 |
| Buriedness | 0.780 |
| Don/acc character | 1.442 |
| SiteScore | 1.205 |
| D Score | 1.027 |
| Kd | — |