Complex 8any
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.85 |
| System mass | 3309.20 kDa |
| Deposition year | 2022 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 8any |
| Reference | Singh Vivek, Moran J. Conor, Itoh Yuzuru, Soto Iliana C., Fontanesi Flavia, Couvillion Mary, Huynen Martijn A., Churchman L. Stirling, Barrientos Antoni, Amunts Alexey. 2024. Structural basis of LRPPRC–SLIRP-dependent translation by the mitoribosome Nature Structural & Molecular Biology |
| Equivalence Class |
NR_all_12763.37,
NR_all_93855.32
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | NAD |
| Residue | . / 1701 |
| Chain | SC / AA |
| Non-redundant | True |
| Interacting RNA chains | A/AA |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | A/AA: rRNA |
| RNA family global | rRNA |
| Volume | 833.49 Å3 |
| Hydrophobicity | 0.235 |
| Hydrophilicity | 1.496 |
| Buriedness | 0.820 |
| Don/acc character | 0.753 |
| SiteScore | 1.081 |
| D Score | 0.944 |
| Kd | — |
| Compound | SPM |
| Residue | . / 1702 |
| Chain | TC / AA |
| Non-redundant | False |
| Interacting RNA chains | A/AA |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | A/AA: rRNA |
| RNA family global | rRNA |
| Volume | 751.86 Å3 |
| Hydrophobicity | 0.176 |
| Hydrophilicity | 1.508 |
| Buriedness | 0.812 |
| Don/acc character | 1.862 |
| SiteScore | 1.227 |
| D Score | 0.936 |
| Kd | — |