Harnessing RIBOnucleic acid - Small molecules Structures
In situ HHT and CHX treated human hibernating state 80S ribosome
SM: 3HE HMT SPM
In situ CHX and HHT treated 80S consensus ribosome
In situ human P state 80S ribosome
SM: SPM
In situ structure of the human mitoribosome in the P state from TACO1-knockout cells
SM: NAD SPM
In situ structure of human mitoribosome in the A/T-P state from TACO1-knockout cells
In situ structure of the human mitoribosome in the A-P state from TACO1-knockout cells
In situ structure of the human mitoribosome in the A/P-P/E state from TACO1-knockout cells
In situ structure of the human mitoribosome in the A/T-P-E state from TACO1-knockout cells
In situ structure of the human mitoribosome in the A-P-E state from TACO1-knockout cells
In situ structure of the human mitoribosome in the A/P-P/E state
SARS-CoV-2 core polymerase complex bound to RNA, araUMP, and UTP
SM: UTP
Structure of dsRNA 16mer containing 4'-C-methyladenosine
Human telomerase catalytic core with shelterin protein TPP1, dTpNHpp and DNA primer ending in AGGG
SM: 1FZ
Human telomerase catalytic core with shelterin protein TPP1, BIBR1532, dTpNHpp and DNA primer ending in AGGG
Human telomerase catalytic core with shelterin protein TPP1, dGpNHpp and DNA primer ending in TTAG
SM: XG4
Class I (T1D0+) of Human telomerase catalytic core with shelterin protein TPP1, BIBR1532, dGpNHpp and DNA primer ending in TTAG
Cryo-EM structure of the 70S ribosome of a MLSb sensitive S. aureus strain "KES34" in complex with solithromycin
SM: EM1
Cryo-EM structure of the A2085-methylated 50S ribosome of a MLSb resistant S. aureus strain "MNY196" in complex with solithromycin
Ternary complex of translating ribosome, NAC and NMT1
Quaternary complex of a translating ribosome, NAC, NMT1, and NatA
Cryo-EM structure of SKM-70S ribosomal stalled complex in the major state (vacant A-site, canon)
SM: A1JA7
Cryo-EM structure of SKM-70S ribosomal stalled complex in the A-tRNA positioned (Body open) state.
SM: A1JAI
Structure of a stalled E. coli 70S RNC-NuoK-86 in complex with the membrane protein insertase SecYEG-YidC
Manikomycin bound to the Escherichia coli 70S ribosome
SM: PAR
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and RBFA (Outward conformation) (State M3)
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15, RBFA, and mtIF2 (State M2.1)
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and RBFA (Inward conformation) (State M2)
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and mS37 (State M4)
SM: NAD
Structure of the ZAK-bound human disome
SM: ANM
Structure of the 70S-EF-G(P610L)-GDP-Pi ribosome complex with tRNAs in hybrid state 1 (H1-EF-G(P610L)-GDP-Pi)
SM: AM2 GDP
Structure of the 70S-EF-G(P610L)-GDP-Pi ribosome complex with tRNAs in hybrid state 2 (H2-EF-G(P610L)-GDP-Pi)
Human mitoribosome bound to TACO1 (Translational activator of COX1), mRNA, A/A-, P/P- and (partial) E/E-tRNAs
WT-HEK 80S ribosome bound to Kozak mRNA (WT-Kozak)
SM: HYG
WT-HEK 80S ribosome bound to TISU mRNA (WT-TISU)
RPS26dC HEK mutant 80S ribosome bound to Kozak mRNA (RPS26dC-Kozak)
SM: ANM HYG
WT-HEK 80S ribosome bound to H2B mRNA (WT-H2B)
Structure at 1.9 A resolution of Thermus thermophilus tyrosyl-tRNA synthetase bound to wild-type modified tRNA(Tyr), tyrosine and AMP
SM: 1PE
Structure at 1.9 A resolution of Thermus thermophilus tyrosyl-tRNA synthetase bound to wild-type tRNATyr(GUC).
Cryo-EM structure of the catalytic core of human telomerase at the initiation state of the repeat addition cycle
SM: 1GC
Cryo-EM structure of the catalytic core of human telomerase at the elongation state of the repeat addition cycle
SM: A1ACD
Cryo-EM structure of the catalytic core of human telomerase at the pre-termination state of the repeat addition cycle
Doxycycline Bound E. coli Ribosome with Rearranged Peptidyl Transferase Centre
SM: DXT
CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING N1-METHYLPSEUDOURIDINE
CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING URIDINE
Cryo-EM structure of SKM-70S ribosomal stalled complex in the rotated state with hybrid tRNAs
30S Doxycycline Bound E. coli Ribosome
Structure of a stalled E. coli 70S RNC-NuoK-70 in complex with the membrane protein insertase SecYEG-YidC
Doxycycline Bound C. burnetii 30S Ribosome
Cryo-EM structure of the 70S ribosome from Francisella tularensis bound to antibiotics chloramphenicol and gentamicin
SM: CLM LLL
DalDro bound to the terminating Escherichia coli 70S ribosome
DalDroS bound to the Escherichia coli 50S ribosomal subunit
Staphylococcus aureus 50S ribosome in complex with RRF, EF-G and fusidic acid (50S-RRF-EF-G-FA)
SM: FUA GDP
Staphylococcus aureus 70S ribosome in complex with RRF, EF-G and fusidic acid (70S-RRF-EF-G-FA)
E. coli 70S ribosome with A- and P-site tRNA
SM: SCM
E. coli 70S ribosome with A/P- and P/E-site tRNA
E. coli 70S ribosome, trapped conformational ground state of SSU-h44 apical loop, with A- and P-site tRNA
Triple Stack Doxycycline Bound 50S Subunit of the Coxiella burnetii Ribosome
70S Coxiella burnetii Ribosome with Doxycycline and HPFcold
INTERACTION BETWEEN A FLUOROQUINOLONE DERIVATIVE AND RNAS WITH A SINGLE BULGE
SM: 53D
Current selection range: to
