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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9qqa

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 2.80
System mass 3954.49 kDa
Deposition year 2025
Molecule type RNA/Protein
# RNA entities 1
Organism Oryctolagus
RCSB PDB Entry 9qqa
Reference Gamerdinger Martin, Echeverria Blanca, Lentzsch Alfred M., Burg Nicolas, Fan Ziyi, Jaskolowski Mateusz, Scaiola Alain, Piening Selina, Shan Shu-ou, Ban Nenad, Deuerling Elke. 2025. Mechanism of cotranslational protein N-myristoylation in human cells Molecular Cell
Equivalence Class NR_all_21280.51, NR_all_06650.50
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound SPM
Residue . / 2044
Chain VH / A2
Non-redundant False
Interacting RNA chains A/A2
RNA environment detailled ion
RNA environment global RNA
RNA family chains A/A2: rRNA
RNA family global rRNA
Volume 766.95 Å3
Hydrophobicity 0.340
Hydrophilicity 0.993
Buriedness 0.780
Don/acc character 2.504
SiteScore 1.214
D Score 1.084
Kd

Compound SPM
Residue . / 5142
Chain MR / B5
Non-redundant True
Interacting RNA chains KA/B5
RNA environment detailled protein
RNA environment global RNA/Protein
RNA family chains KA/B5: rRNA
RNA family global rRNA
Volume 225.35 Å3
Hydrophobicity 0.000
Hydrophilicity 1.359
Buriedness 0.688
Don/acc character 1.809
SiteScore 0.813
D Score 0.679
Kd

Compound SPM
Residue . / 5143
Chain NR / B5
Non-redundant True
Interacting RNA chains KA/B5
RNA environment detailled protein, ion
RNA environment global RNA/Protein
RNA family chains KA/B5: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd