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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9q10

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 2.90
System mass 328.01 kDa
Deposition year 2025
Molecule type RNA/DNA/Protein
# RNA entities 1
Organism Homo
RCSB PDB Entry 9q10
Equivalence Class NR_all_91211.4
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound 1FZ
Residue . / 1201
Chain G / A
Non-redundant True
Interacting RNA chains A/B
RNA environment detailled DNA, protein
RNA environment global RNA/DNA/Protein
RNA family chains A/B: telomerase_RNA
RNA family global telomerase_RNA
Volume 402.00 Å3
Hydrophobicity 0.240
Hydrophilicity 1.456
Buriedness 0.804
Don/acc character 0.579
SiteScore 1.071
D Score 0.948
Kd