Harnessing RIBOnucleic acid - Small molecules Structures
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Closed Mtb-EC: Cryo-EM structure of Mtb RNAP elongation complex (substrate loading mimic) with a closed active site (closed TL and RH-FL)
SM: GTP
SemiClosed Mtb-EC: Cryo-EM structure of Mtb RNAP elongation complex (substrate loading mimic) with a semiclosed active site (closed TL, open RH-FL)
AAP-SO2 bound Open Mtb-EC: Cryo-EM structure of Mtb RNAP elongation complex (substrate loading mimic) with an open active site (open TL and RH-FL)
NMR structure and free-energy simulations for rational design of myotonic dystrophy RNA inhibitors
SM: A1DA4
SARS-CoV-2 RNA-dependent RNA polymerase in complex with 4'-FlA nucleotide analogue
SM: A1DCZ
SATELLITE TOBACCO MOSAIC VIRUS/RNA COMPLEX
SM: U5P
VACCINIA METHYLTRANSFERASE VP39 COMPLEXED WITH M7G CAPPED RNA HEXAMER AND S-ADENOSYLHOMOCYSTEINE
SM: SAH
X-RAY CRYSTAL STRUCTURE OF THE POLY(A)-BINDING PROTEIN IN COMPLEX WITH POLYADENYLATE RNA
SM: AMP AMP AMP AMP AMP AMP AMP AMP
THEOPHYLLINE-BINDING RNA IN COMPLEX WITH THEOPHYLLINE, NMR, 10 STRUCTURES
SM: TEP
CRYSTAL STRUCTURE OF A BIOTIN-BINDING RNA PSEUDOKNOT
SM: BTN
CRYSTAL STRUCTURE OF A 14BP RNA OLIGONUCLEOTIDE CONTAINING DOUBLE UU BULGES: A NOVEL INTRAMOLECULAR U*(AU) BASE TRIPLE
SM: SPM
CRYSTAL STRUCTURE OF AN SM-LIKE PROTEIN (AF-SM1) FROM ARCHAEOGLOBUS FULGIDUS COMPLEXED WITH SHORT POLY-U RNA
SM: URI
X-ray Analysis of a RNA Tetraplex r(uggggu)4 at Ultra-High Resolution
Crystal Structure of the B-DNA Hexamer (CgATCG).Daunomycin Complex Containing a Ribose at the Intercalation Site
SM: DM1
Initiation complex of polymerase lambda3 from reovirus
SM: CH1 GH3
lambda3 elongation complex with four phosphodiester bond formed
SM: CH1
reovirus polymerase lambda3 elongation complex with one phosphodiester bond formed
SM: U3H
THEOPHYLLINE-BINDING RNA IN COMPLEX WITH THEOPHYLLINE, NMR, REGULARIZED MEAN STRUCTURE, REFINEMENT WITH TORSION ANGLE AND BASE-BASE POSITIONAL DATABASE POTENTIALS AND DIPOLAR COUPLINGS
Structural basis for substrate selection by T7 RNA polymerase
SM: APC APC APC APC
T7 RNA polymerase alpha beta methylene ATP elongation complex
SM: APC
Complete RNA Polymerase II elongation complex with substrate analogue GMPCPP
SM: G2P
A solution NMR model of L-RNA r(UAGGGUUAGGGU) bounding Protoporphyrin IX ligand
SM: PP9
Structure of Yeast RNA polymerase II elongation complex with NTP-state-III
RNA polymerase II elongation complex at 5 mM Mg2+ with GTP
Foot-and-mouth disease virus RNA-dependent RNA polymerase in complex with a template-primer RNA and with ribavirin
SM: RTP
Foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA, ATP and UTP
SM: UTP
Structure of T4 RNA Ligase 2 with Nicked 5'-Adenylated nucleic acid duplex containing a 3'-deoxyribonucleotide at the nick
SM: BTB
Crystal structure of an H/ACA box RNP from Pyrococcus furiosus
SM: ATP
Solution structure and thermodynamics of 2',5' RNA intercalation
SM: PRL PRL
Solution structure of small molecule-influenza RNA complex
SM: 0EC
RNA Polymerase II Elongation Complex in 150 mM Mg+2 with GMPCPP
RNA polymerase II elongation complex in 5 mM Mg+2 with 2'-dUTP
SM: DUT
Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the NTP substrate analog
SM: APC APC
Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the ntp substrate analog and antibiotic streptolydigin
Structure of Yeast Poly(A) Polymerase with ATP and oligo(A)
Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in State III (TL-open), in the presence of substrate ATP
Cryo-EM structure of the yeast RNA polymerase II elongation complex with 19-mer RNA in State V (TL-closed), in the presence of substrate ATP
Cryo-EM structure of the E. coli DRT10 RT-ncRNA complex, Eco3 subtype with dNTPs
SM: DGT DTP
Structure of viral RNA polymerase complex 1
SM: GH3 GH3
Structure of viral RNA polymerase complex 4
SM: GH3
Structure of viral RNA polymerase complex 5
Structure of viral RNA polymerase complex 6
Norwalk Virus polymerase bound to 5-nitrocytidine triphosphate and primer-template RNA
SM: N5C
Norwalk Virus polymerase bound to cytidine 5'-triphosphate and primer-template RNA
SM: CTP
Crystal Structure of 2'-amino-2'-deoxy-cytidine-5'-triphosphate bound to Norovirus GII RNA polymerase
SM: CSG
Norovirus polymerase+primer/template+CTP complex at 6 mM MnCl2
Crystal structure of a substrate-bound Gar1-minus H/ACA RNP from Pyrococcus furiosus
SM: PG4
Crystal structure of small RNA methyltransferase HEN1
SM: SAH SAH
In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus
Puf3 RNA binding domain bound to Cox17 RNA 3' UTR recognition sequence site B
SM: CIT CIT
Poliovirus polymerase elongation complex with 2'-deoxy-CTP
SM: DCP DCP
Poliovirus polymerase elongation complex with 2',3'-dideoxy-ctp
SM: DCT DCT DCT DCT
RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with ATP
RNA Polymerase II Initiation Complex with a 5-nt 3'-deoxy RNA soaked with GTP
Crystal structure of PUF-6 in complex with 5BE13 RNA
SM: EPE
Complex structure of viral RNA polymerase I
Complex structure of viral RNA polymerase II
RNA Polymerase II initial transcribing complex with a 5nt DNA-RNA hybrid and soaked with AMPCPP
RNA Polymerase II initial transcribing complex with a 6nt DNA-RNA hybrid and soaked with AMPCPP
RNA Polymerase II initial transcribing complex with a 7nt DNA-RNA hybrid and soaked with AMPCPP
Current selection range: to
Filter entries " Experimental resolution " between the two values. Global DB range: 0.6 – 11.2
Filter entries " Molecular weight (compound) " between the two values. Global DB range: 150 – 1000
Filter entries " Deposition date " between the two values. Global DB range: 1986 – 2027
Filter entries " Molecular weight (complex) " between the two values. Global DB range: 0 – 13090
Filter entries " Number of atoms " between the two values. Global DB range: 5 – 70
Filter entries " Number of interacting chains " between the two values. Global DB range: 1 – 4
Filter entries " Pocket size " between the two values. Global DB range: 15.9 – 394.0
Filter entries " SiteScore " between the two values. Global DB range: 0.3 – 1.3
Filter entries " Dscore " between the two values. Global DB range: -0.1 – 1.4
Filter entries " Exposure " between the two values. Global DB range: 0.1 – 1.0
Filter entries " Enclosure " between the two values. Global DB range: 0.3 – 1.0
Filter entries " Hydrophobicity " between the two values. Global DB range: 0.0 – 3.1
Filter entries " Hydrophilicity " between the two values. Global DB range: 0.2 – 2.8
Filter entries " Donor/Acceptor " between the two values. Global DB range: 0.0 – 5.0
Filter entries " Volume " between the two values. Global DB range: 21.2 – 1528.8