Complex 3avt

Legend

Pocket colors by molecule type

RNA

Protein

DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique	X-ray
Experimental resolution	2.61
System mass	144.69 kDa
Deposition year	2011
Molecule type	RNA/Protein
# RNA entities	1
Organism	N/A
RCSB PDB Entry	3avt
Reference	Takeshita Daijiro, Tomita Kozo. 2012. Molecular basis for RNA polymerization by Qβ replicase Nature Structural & Molecular Biology
Equivalence Class	NR_all_75747.1 BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

Favourable

Intermediate

Unfavourable

Not available

Score	Threshold	Meaning
SiteScore	< 0.8	Non-drug binding site
SiteScore	0.8 – 1.0	Potential drug binding site
SiteScore	> 1.0	Promising binding site
D Score	< 0.83	Undruggable
D Score	0.83 – 0.98	Difficult
D Score	> 0.98	Druggable

Tick a pocket below to highlight it in the 3D structure above.

Pocket 1

Compound	GH3
Residue	. / 2502
Chain	C / A
Non-redundant	False
Interacting RNA chains	B/T
RNA environment detailled	protein, ion, other
RNA environment global	RNA/Other
RNA family chains	B/T: unknown
RNA family global	unknown
Volume	722.02 Å³
Hydrophobicity	0.174
Hydrophilicity	1.485
Buriedness	0.815
Don/acc character	0.775
SiteScore	1.078
D Score	0.945
Kd	—

Pocket 2

Compound	GH3
Residue	. / 2501
Chain	F / T
Non-redundant	False
Interacting RNA chains	B/T
RNA environment detailled	protein, ion, other
RNA environment global	RNA/Other
RNA family chains	B/T: unknown
RNA family global	unknown
Volume	531.31 Å³
Hydrophobicity	0.427
Hydrophilicity	1.282
Buriedness	0.786
Don/acc character	1.134
SiteScore	1.059
D Score	0.994
Kd	—