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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 3htx

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 3.10
System mass 240.03 kDa
Deposition year 2009
Molecule type RNA/Protein
# RNA entities 1
Organism N/A
RCSB PDB Entry 3htx
Reference Huang Ying, Ji Lijuan, Huang Qichen, Vassylyev Dmitry G., Chen Xuemei, Ma Jin-Biao. 2009. Structural insights into mechanisms of the small RNA methyltransferase HEN1 Nature
Equivalence Class NR_all_47541.3
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound SAH
Residue . / 951
Chain H / A
Non-redundant True
Interacting RNA chains B/B, C/C
RNA environment detailled protein, ion
RNA environment global RNA/Protein
RNA family chains B/B: unknown, C/C: unknown
RNA family global unknown
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound SAH
Residue . / 951
Chain J / D
Non-redundant False
Interacting RNA chains E/E, F/F
RNA environment detailled protein, ion
RNA environment global RNA/Protein
RNA family chains E/E: unknown, F/F: unknown
RNA family global unknown
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd