Complex 3olb
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.41 |
| System mass | 281.11 kDa |
| Deposition year | 2010 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 3olb |
| Reference | Gong Peng, Peersen Olve B.. 2010. Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase Proceedings of the National Academy of Sciences |
| Equivalence Class |
NR_all_48488.2
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | DCT |
| Residue | . / 4004 |
| Chain | R / A |
| Non-redundant | True |
| Interacting RNA chains | B/B, C/C |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | B/B: unknown, C/C: unknown |
| RNA family global | unknown |
| Volume | 277.14 Å3 |
| Hydrophobicity | 0.533 |
| Hydrophilicity | 1.226 |
| Buriedness | 0.858 |
| Don/acc character | 0.388 |
| SiteScore | 0.897 |
| D Score | 0.786 |
| Kd | — |
| Compound | DCT |
| Residue | . / 4003 |
| Chain | V / E |
| Non-redundant | False |
| Interacting RNA chains | F/F, G/G |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | F/F: unknown, G/G: unknown |
| RNA family global | unknown |
| Volume | 333.05 Å3 |
| Hydrophobicity | 0.368 |
| Hydrophilicity | 1.292 |
| Buriedness | 0.857 |
| Don/acc character | 0.510 |
| SiteScore | 0.941 |
| D Score | 0.821 |
| Kd | — |
| Compound | DCT |
| Residue | . / 4002 |
| Chain | BA / I |
| Non-redundant | False |
| Interacting RNA chains | J/J, K/K |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | J/J: unknown, K/K: unknown |
| RNA family global | unknown |
| Volume | 464.42 Å3 |
| Hydrophobicity | 0.200 |
| Hydrophilicity | 1.446 |
| Buriedness | 0.830 |
| Don/acc character | 0.891 |
| SiteScore | 0.951 |
| D Score | 0.790 |
| Kd | — |
| Compound | DCT |
| Residue | . / 4001 |
| Chain | GA / M |
| Non-redundant | False |
| Interacting RNA chains | O/O, N/N |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | N/N: unknown, O/O: unknown |
| RNA family global | unknown |
| Volume | 318.65 Å3 |
| Hydrophobicity | 0.395 |
| Hydrophilicity | 1.351 |
| Buriedness | 0.839 |
| Don/acc character | 0.579 |
| SiteScore | 0.910 |
| D Score | 0.766 |
| Kd | — |