Complex 3j5l
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 6.60 |
| System mass | 1346.00 kDa |
| Deposition year | 2013 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 3j5l |
| Reference | Arenz Stefan, Ramu Haripriya, Gupta Pulkit, Berninghausen Otto, Beckmann Roland, Vázquez-Laslop Nora, Mankin Alexander S., Wilson Daniel N.. 2014. Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide Nature Communications |
| Equivalence Class |
NR_all_83717.187
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | ERY |
| Residue | . / 9000 |
| Chain | JA / A |
| Non-redundant | True |
| Interacting RNA chains | I/A |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | I/A: rRNA |
| RNA family global | rRNA |
| Volume | 525.48 Å3 |
| Hydrophobicity | 0.216 |
| Hydrophilicity | 1.150 |
| Buriedness | 0.794 |
| Don/acc character | 1.489 |
| SiteScore | 1.120 |
| D Score | 0.921 |
| Kd | — |