Complex 1s0v
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.20 |
| System mass | 447.71 kDa |
| Deposition year | 2004 |
| Molecule type | RNA/DNA/Protein |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 1s0v |
| Reference | Temiakov Dmitry, Patlan Vsevolod, Anikin Michael, McAllister William T, Yokoyama Shigeyuki, Vassylyev Dmitry G. 2004. Structural Basis for Substrate Selection by T7 RNA Polymerase Cell |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | APC |
| Residue | . / 2000 |
| Chain | S / A |
| Non-redundant | True |
| Interacting RNA chains | B/F |
| RNA environment detailled | DNA, protein, ion |
| RNA environment global | RNA/DNA/Protein |
| RNA family chains | B/F: unknown |
| RNA family global | unknown |
| Volume | 420.52 Å3 |
| Hydrophobicity | 0.449 |
| Hydrophilicity | 1.184 |
| Buriedness | 0.816 |
| Don/acc character | 0.689 |
| SiteScore | 1.079 |
| D Score | 1.044 |
| Kd | — |
| Compound | APC |
| Residue | . / 2001 |
| Chain | V / B |
| Non-redundant | True |
| Interacting RNA chains | E/I |
| RNA environment detailled | DNA, protein, ion |
| RNA environment global | RNA/DNA/Protein |
| RNA family chains | E/I: unknown |
| RNA family global | unknown |
| Volume | 415.03 Å3 |
| Hydrophobicity | 0.648 |
| Hydrophilicity | 1.072 |
| Buriedness | 0.824 |
| Don/acc character | 0.719 |
| SiteScore | 1.084 |
| D Score | 1.085 |
| Kd | — |
| Compound | APC |
| Residue | . / 2002 |
| Chain | Y / C |
| Non-redundant | True |
| Interacting RNA chains | H/L |
| RNA environment detailled | DNA, protein, ion |
| RNA environment global | RNA/DNA/Protein |
| RNA family chains | H/L: unknown |
| RNA family global | unknown |
| Volume | 547.77 Å3 |
| Hydrophobicity | 0.190 |
| Hydrophilicity | 1.311 |
| Buriedness | 0.793 |
| Don/acc character | 0.866 |
| SiteScore | 1.064 |
| D Score | 0.989 |
| Kd | — |
| Compound | APC |
| Residue | . / 2003 |
| Chain | BA / D |
| Non-redundant | True |
| Interacting RNA chains | K/O |
| RNA environment detailled | DNA, protein, ion |
| RNA environment global | RNA/DNA/Protein |
| RNA family chains | K/O: unknown |
| RNA family global | unknown |
| Volume | 449.33 Å3 |
| Hydrophobicity | 0.513 |
| Hydrophilicity | 1.217 |
| Buriedness | 0.808 |
| Don/acc character | 0.970 |
| SiteScore | 1.074 |
| D Score | 1.028 |
| Kd | — |