Harnessing RIBOnucleic acid - Small molecules Structures
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E. coli mutant sigma-S transcription initiation complex with an 8-nt RNA ("Fresh" mutant crystal soaked with GTP, UTP, CTP, and ddATP for 30 minutes)
SM: 2DA
E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching ATP ("Fresh" crystal soaked with ATP for 2 hours)
SM: ATP
Cryo-EM structure of the Acinetobacter baumannii Ribosome: 70S with P-site tRNA
SM: FME
Co-crystal structure of the fluorogenic Mango-IV homodimer bound to TO1-Biotin
SM: QSA QSA QSA
SM: QW4 QW4 QW4
Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MH5
SM: QSV
Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MQC
SM: MQC
Solution Structure of the Tau pre-mRNA Exon 10 Splicing Regulatory Element Bound to MIP
SM: QSY
Metabolite-bound PreQ1 riboswitch with Mn2+
SM: PRF
CryoEM structure of yeast 80S ribosome with Met-tRNAiMet, eIF5B, and GDP
SM: GDP
Thermus thermophilus RNA polymerase initially transcribing complex with 2'dCTP
SM: DCP
Thermus thermophilus RNA polymerase initially transcribing complex with 3'dCTP
SM: CH1
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, contezolid
SM: ZC0
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, radezolid
SM: RD8
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with the antibiotic, tedizolid
SM: U7V
Structure of the 50S subunit of the ribosome from Methicillin Resistant Staphylococcus aureus in complex with an isomer of the tedizolid
SM: U7Y
Structure of Human pir-miRNA-19b-2 Apical Loop and One-base-pair Fused to the YdaO Riboswitch Scaffold
SM: 2BA 2BA
Structure of Human pir-miRNA-300 Apical Loop Fused to the YdaO Riboswitch Scaffold
E. coli 50S ribosome bound to compounds 47 and VS1
SM: O7S
Fusibacterium ulcerans ZTP riboswitch bound to p-1-pyridinyl AICA
SM: UG1 UG1
Fusibacterium ulcerans ZTP riboswitch bound to m-1-pyridinyl AICA
SM: UG4 UG4
Structure of a drug-like compound stalled human translation termination complex
SM: MVM
IRES-targeting Small Molecule Inhibits Enterovirus 71 Replication via Allosteric Stabilization of a Ternary Complex
SM: UYS
Crystal structure of the A2058-unmethylated Thermus thermophilus 70S ribosome in complex with erythromycin and protein Y (YfiA) at 2.55A resolution
SM: ARG ARG ERY ERY
Crystal structure of the Thermus thermophilus 70S ribosome in complex with telithromycin, mRNA, aminoacylated A- and P-site tRNAs, and deacylated E-site tRNA at 2.60A resolution
SM: TEL TEL
Crystal structure of eIF4A-I in complex with RNA bound to des-MePateA, a pateamine A analog
SM: V6D
Class III PreQ1 riboswitch mutant A52G
Class III PreQ1 riboswitch mutant A84G
Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UUC-mRNA, and deacylated P-site tRNA at 2.80A resolution
SM: V7A V7A
Crystal structure of the Thermus thermophilus 70S ribosome in complex with sarecycline, UAA-mRNA, and deacylated P-site tRNA at 3.00A resolution
Structural descriptions of ligand interactions to DNA and RNA quadruplexes folded from the non-coding region of Pseudorabies virus
SM: V8A V8A
E. coli 50S ribosomal subunit in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet).
SM: DI0
E. coli 70S ribosome in complex with dirithromycin, and deacylated tRNA(iMet) (focused classification).
E. coli 70S ribosome in complex with dirithromycin, fMet-Phe-tRNA(Phe) and deacylated tRNA(iMet) (focused classification).
Structure of human ribosome in classical-PRE state
SM: 3HE
Structure of human ribosome in POST state
Cryo-EM structure of an Escherichia coli 70S ribosome in complex with antibiotic TetracenomycinX
SM: OCW
Tetracenomycin X bound to the human ribosome
55S mammalian mitochondrial ribosome with mtEFG1 and P site fMet-tRNAMet (POST)
SM: 5GP 5GP GNP SPM SPM SPM
55S mammalian mitochondrial ribosome with mtEFG1 and two tRNAMet (TI-POST)
SM: 5GP GNP SPM SPM SPM
Crystal structure of the SAM-SAH riboswitch with SAH
SM: SAH SAH SAH SAH SAH SAH SAH SAH SAH
Crystal structure of the SAM-SAH riboswitch with SAM
SM: SAM SAM SAM SAM SAM SAM SAM SAM SAM
Rix1-Rea1 pre-60S particle - 60S core, body 1 (rigid body refinement)
SM: GTP
Rix1-Rea1 pre-60S particle - full composite structure
Crystal structure of the SAM-SAH riboswitch with AMP.
SM: AMP AMP AMP AMP AMP AMP AMP AMP AMP CBV CBV
Crystal structure of the SAM-SAH riboswitch with adenosine.
SM: ADN ADN ADN ADN ADN ADN ADN ADN ADN
Crystal structure of the SAM-SAH riboswitch with AMP
SM: MTA MTA MTA MTA MTA MTA MTA MTA MTA
Crystal structure of the SAM-SAH riboswitch with decarboxylated SAH
SM: AMP DSH DSH
Crystal structure of the SAM-SAH riboswitch with SAM from space group P312
SM: SAM SAM SAM
Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex
SM: P5E
Acinetobacter baumannii ribosome-amikacin complex - 30S subunit body
SM: AKN
Acinetobacter baumannii ribosome-tigecycline complex - 50S subunit
SM: T1C T1C T1C
Acinetobacter baumannii ribosome-tigecycline complex - 30S subunit head
SM: T1C
The structure of the mitoribosome from Neurospora crassa in the P/E tRNA bound state
SM: NAD SPM
The structure of the large subunit of the mitoribosome from Neurospora crassa
The structure of the Atp25 bound assembly intermediate of the mitoribosome from Neurospora crassa
The structure of the mitoribosome from Neurospora crassa with tRNA bound to the E-site
The structure of the mitoribosome from Neurospora crassa with bound tRNA at the P-site
Human mitochondrial ribosome in complex with ribosome recycling factor
SM: DOL
Human mitochondrial ribosome bound to mRNA, A-site tRNA and P-site tRNA
Current selection range: to
Filter entries " Experimental resolution " between the two values. Global DB range: 0.6 – 11.2
Filter entries " Molecular weight (compound) " between the two values. Global DB range: 150 – 1000
Filter entries " Deposition date " between the two values. Global DB range: 1986 – 2027
Filter entries " Molecular weight (complex) " between the two values. Global DB range: 0 – 13090
Filter entries " Number of atoms " between the two values. Global DB range: 5 – 70
Filter entries " Number of interacting chains " between the two values. Global DB range: 1 – 4
Filter entries " Pocket size " between the two values. Global DB range: 15.9 – 394.0
Filter entries " SiteScore " between the two values. Global DB range: 0.3 – 1.3
Filter entries " Dscore " between the two values. Global DB range: -0.1 – 1.4
Filter entries " Exposure " between the two values. Global DB range: 0.1 – 1.0
Filter entries " Enclosure " between the two values. Global DB range: 0.3 – 1.0
Filter entries " Hydrophobicity " between the two values. Global DB range: 0.0 – 3.1
Filter entries " Hydrophilicity " between the two values. Global DB range: 0.2 – 2.8
Filter entries " Donor/Acceptor " between the two values. Global DB range: 0.0 – 5.0
Filter entries " Volume " between the two values. Global DB range: 21.2 – 1528.8