Harnessing RIBOnucleic acid - Small molecules Structures
Quaternary complex of a translating ribosome, NAC, NMT1, and NatA
SM: SPM
Cryo-EM structure of SKM-70S ribosomal stalled complex in the major state (vacant A-site, canon)
SM: A1JA7
Cryo-EM structure of SKM-70S ribosomal stalled complex in the A-tRNA positioned (Body open) state.
SM: A1JAI
Structure of a stalled E. coli 70S RNC-NuoK-86 in complex with the membrane protein insertase SecYEG-YidC
Manikomycin bound to the Escherichia coli 70S ribosome
SM: PAR
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and RBFA (Outward conformation) (State M3)
SM: NAD SPM
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15, RBFA, and mtIF2 (State M2.1)
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and RBFA (Inward conformation) (State M2)
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and mS37 (State M4)
SM: NAD
Structure of the ZAK-bound human disome
SM: ANM
Structure of the 70S-EF-G(P610L)-GDP-Pi ribosome complex with tRNAs in hybrid state 1 (H1-EF-G(P610L)-GDP-Pi)
SM: AM2 GDP
Structure of the 70S-EF-G(P610L)-GDP-Pi ribosome complex with tRNAs in hybrid state 2 (H2-EF-G(P610L)-GDP-Pi)
Human mitoribosome bound to TACO1 (Translational activator of COX1), mRNA, A/A-, P/P- and (partial) E/E-tRNAs
WT-HEK 80S ribosome bound to Kozak mRNA (WT-Kozak)
SM: HYG
WT-HEK 80S ribosome bound to TISU mRNA (WT-TISU)
RPS26dC HEK mutant 80S ribosome bound to Kozak mRNA (RPS26dC-Kozak)
SM: ANM HYG
WT-HEK 80S ribosome bound to H2B mRNA (WT-H2B)
Structure at 1.9 A resolution of Thermus thermophilus tyrosyl-tRNA synthetase bound to wild-type modified tRNA(Tyr), tyrosine and AMP
SM: 1PE
Structure at 1.9 A resolution of Thermus thermophilus tyrosyl-tRNA synthetase bound to wild-type tRNATyr(GUC).
Doxycycline Bound E. coli Ribosome with Rearranged Peptidyl Transferase Centre
SM: DXT
CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING N1-METHYLPSEUDOURIDINE
CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING URIDINE
Cryo-EM structure of SKM-70S ribosomal stalled complex in the rotated state with hybrid tRNAs
30S Doxycycline Bound E. coli Ribosome
Structure of a stalled E. coli 70S RNC-NuoK-70 in complex with the membrane protein insertase SecYEG-YidC
Doxycycline Bound C. burnetii 30S Ribosome
Cryo-EM structure of the 70S ribosome from Francisella tularensis bound to antibiotics chloramphenicol and gentamicin
SM: CLM LLL
DalDro bound to the terminating Escherichia coli 70S ribosome
DalDroS bound to the Escherichia coli 50S ribosomal subunit
Staphylococcus aureus 50S ribosome in complex with RRF, EF-G and fusidic acid (50S-RRF-EF-G-FA)
SM: FUA GDP
Staphylococcus aureus 70S ribosome in complex with RRF, EF-G and fusidic acid (70S-RRF-EF-G-FA)
E. coli 70S ribosome with A- and P-site tRNA
SM: SCM
E. coli 70S ribosome with A/P- and P/E-site tRNA
E. coli 70S ribosome, trapped conformational ground state of SSU-h44 apical loop, with A- and P-site tRNA
Triple Stack Doxycycline Bound 50S Subunit of the Coxiella burnetii Ribosome
70S Coxiella burnetii Ribosome with Doxycycline and HPFcold
SARS-CoV-2 E-RTC in complex with RNA-nsp9 and GMPPNP
SM: GNP
human mitoribosome trapped by retapamulin
SM: G34 NAD
Cryo- EM structure of 75S ribosome with A/P- & P/E- tRNAs from Entamoeba histolytica bound to antibiotic paromomycin
Cryo- EM structure of small subunit (body) of 75S ribosome with A/P- & P/E- tRNAs from Entamoeba histolytica bound to antibiotic paromomycin
Human mitoribosome in a non-rotated state, with multiple neomycin molecules bound, featuring A/A-site and P/P-site tRNAs
SM: NAD NMY SPM
Human cytosolic ribosome in a rotated state, with multiple neomycin molecules bound, featuring A/P-site and P/E-site tRNAs
SM: NMY
Crimean-Congo hemorrhagic fever virus RNA polymerase containing a 10-bp RNA product and incorporated 2FC
SM: 2KH
Crimean-Congo hemorrhagic fever virus RNA polymerase containing a 10-bp RNA product and incorporated cytidine
Crimean-Congo hemorrhagic fever virus RNA polymerase containing a 15-bp RNA product
Crimean-Congo hemorrhagic fever virus RNA polymerase containing a 9-bp RNA product
CryoEM structure of human NSUN2(C271A) with SAH cross-linked to tRNA Lys(CTT) (D-arm conformation)
SM: SAH
CryoEM structure of human NSUN2(C271A) with SAH cross-linked to tRNA Lys(CTT) (No D-arm conformation)
CryoEM structure of human NSUN2 with tRNA Lys(CTT) and SFG (D-arm conformation)
SM: SFG
CryoEM structure of human NSUN2 with tRNA Lys(CTT) and SFG (No D-arm conformation)
CryoEM structure of human NSUN2(C271A) with SAH cross-linked to tRNA Lys(TTT) (D-arm conformation)
CryoEM structure of human NSUN2(C271A) with SAH cross-linked to tRNA Lys(TTT) (No D-arm conformation)
CryoEM structure of human NSUN2(C271A) with SAH cross-linked to a pre-tRNA Leu(CAA) intron
Current selection range: to
