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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9tey

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 3.11
System mass 2247.04 kDa
Deposition year 2025
Molecule type RNA/Protein
# RNA entities 1
Organism Escherichia
RCSB PDB Entry 9tey
Reference Huang Weiping, Berger Max J., Safdari Haaris A., Klepacki Dorota, Paternoga Helge, Baliga Chetana, Wilson Daniel N., Vázquez-Laslop Nora, Mankin Alexander S.. 2026. Flipping antimicrobial peptides in the exit tunnel of the bacterial ribosome Nature Communications
Equivalence Class NR_all_83717.187
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound SPM
Residue . / 3001
Chain GB / V
Non-redundant True
Interacting RNA chains BB/V
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains BB/V: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd