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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9sul

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 2.10
System mass 3684.28 kDa
Deposition year 2025
Molecule type RNA/Protein
# RNA entities 1
Organism Trypanosoma
RCSB PDB Entry 9sul
Equivalence Class NR_all_25291.4, NR_all_82892.3
BGSU version: 4.61

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound GET
Residue . / 2304
Chain OC / AA
Non-redundant True
Interacting RNA chains L/AA
RNA environment detailled ion
RNA environment global RNA
RNA family chains L/AA: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd —

Compound GET
Residue . / 2370
Chain CF / AA
Non-redundant True
Interacting RNA chains L/AA
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains L/AA: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd —

Compound GET
Residue . / 2372
Chain EF / AA
Non-redundant True
Interacting RNA chains KA/BA, L/AA
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains L/AA: rRNA, KA/BA: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd —

Compound GTP
Residue . / 2309
Chain TC / AA
Non-redundant True
Interacting RNA chains L/AA
RNA environment detailled ion, other
RNA environment global RNA/Other
RNA family chains L/AA: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd —