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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9s7c

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 3.20
System mass 3114.23 kDa
Deposition year 2025
Molecule type RNA/Protein
# RNA entities 1
Organism Homo
RCSB PDB Entry 9s7c
Reference Schöndorf Thomas, Petrychenko Valentyn, Kotan Ilgin, Dahal Drishan, Napieraj Natalia, Cruz-Zaragoza Luis Daniel, Wang Cong, Urbach Oliver, Gall Tanja, Dennerlein Sven, Kramer Günter, Fischer Niels, Rehling Peter. 2026. Membrane insertion of mitochondrial-encoded proteins regulates ribosome decoding speed Nature Structural & Molecular Biology
Equivalence Class NR_all_93855.32
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound NAD
Residue . / 1002
Chain GJ / AA
Non-redundant True
Interacting RNA chains Y/AA
RNA environment detailled protein, ion
RNA environment global RNA/Protein
RNA family chains Y/AA: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd