Harnessing RIBOnucleic acid - Small molecules Structures
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CryoEM structure of transcribing RNA polymerase II elongation complex
SM: ATP
Cryo-EM structure of the 70S ribosome of a MLSb sensitive S. aureus strain "KES34" in complex with solithromycin
SM: EM1
Cryo-EM structure of the A2085-methylated 50S ribosome of a MLSb resistant S. aureus strain "MNY196" in complex with solithromycin
Ternary complex of translating ribosome, NAC and NMT1
SM: SPM SPM SPM
Quaternary complex of a translating ribosome, NAC, NMT1, and NatA
Cryo-EM structure of SKM-70S ribosomal stalled complex in the major state (vacant A-site, canon)
SM: A1JA7
Cryo-EM structure of SKM-70S ribosomal stalled complex in the A-tRNA positioned (Body open) state.
SM: A1JAI
Structure of Yeast RNA polymerase II elongation complex with ATP frame-14
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and RBFA (Outward conformation) (State M3)
SM: NAD SPM
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15, RBFA, and mtIF2 (State M2.1)
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and RBFA (Inward conformation) (State M2)
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and mS37 (State M4)
SM: NAD
Structure of the ZAK-bound human disome
SM: ANM
Structure of the 70S-EF-G(P610L)-GDP-Pi ribosome complex with tRNAs in hybrid state 1 (H1-EF-G(P610L)-GDP-Pi)
SM: AM2 AM2 AM2 GDP
Structure of the 70S-EF-G(P610L)-GDP-Pi ribosome complex with tRNAs in hybrid state 2 (H2-EF-G(P610L)-GDP-Pi)
Human mitoribosome bound to TACO1 (Translational activator of COX1), mRNA, A/A-, P/P- and (partial) E/E-tRNAs
WT-HEK 80S ribosome bound to Kozak mRNA (WT-Kozak)
SM: HYG
WT-HEK 80S ribosome bound to TISU mRNA (WT-TISU)
RPS26dC HEK mutant 80S ribosome bound to Kozak mRNA (RPS26dC-Kozak)
SM: ANM HYG
Structure of human mitochondrial COX1-translating ribosome nascent chain complex with tRNAs in intermediate state (AP*)
Structure of human mitochondrial COX1-translating ribosome nascent chain complex with tRNAs in initial hybrid state (H1)
Structure of human mitochondrial COX1-translating ribosome nascent chain-OXA1L/MITRAC complex in open state (open COX1-mtRNC-OXA1L/MITRAC)
Structure of human mitochondrial COX1-translating ribosome nascent chain-OXA1L/MITRAC complex in closed state (closed COX1-mtRNC-OXA1L/MITRAC)
Structure of Yeast RNA polymerase II elongation complex with ATP frame-7
Structure of Yeast RNA polymerase II elongation complex with ATP frame-8
Structure of Yeast RNA polymerase II elongation complex with ATP frame-9
Structure of Yeast RNA polymerase II elongation complex with ATP frame-10
Structure of Yeast RNA polymerase II elongation complex with ATP frame-11
Structure of Yeast RNA polymerase II elongation complex with ATP frame-12
Structure of Yeast RNA polymerase II elongation complex with ATP frame-13
Structure of Yeast RNA polymerase II elongation complex with ATP frame-19
Structure of Yeast RNA polymerase II elongation complex with ATP frame-20
Structure at 1.9 A resolution of Thermus thermophilus tyrosyl-tRNA synthetase bound to wild-type modified tRNA(Tyr), tyrosine and AMP
SM: 1PE
Structure at 1.9 A resolution of Thermus thermophilus tyrosyl-tRNA synthetase bound to wild-type tRNATyr(GUC).
SM: 1PE 1PE
Cryo-EM structure of the catalytic core of human telomerase at the initiation state of the repeat addition cycle
SM: 1GC
Cryo-EM structure of the catalytic core of human telomerase at the elongation state of the repeat addition cycle
SM: A1ACD
Cryo-EM structure of the catalytic core of human telomerase at the pre-termination state of the repeat addition cycle
Doxycycline Bound E. coli Ribosome with Rearranged Peptidyl Transferase Centre
SM: DXT
CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING N1-METHYLPSEUDOURIDINE
CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING URIDINE
Cryo-EM structure of SKM-70S ribosomal stalled complex in the rotated state with hybrid tRNAs
CryoEM structure of transcribing RNA polymerase II elongation complex with ATP and Elf1
30S Doxycycline Bound E. coli Ribosome
Structure of a stalled E. coli 70S RNC-NuoK-70 in complex with the membrane protein insertase SecYEG-YidC
SM: SPM
Triple Stack Doxycycline Bound 50S Subunit of the Coxiella burnetii Ribosome
SM: DXT DXT DXT
Doxycycline Bound C. burnetii 30S Ribosome
Cryo-EM structure of the 70S ribosome from Francisella tularensis bound to antibiotics chloramphenicol and gentamicin
SM: CLM LLL LLL LLL LLL LLL LLL LLL LLL LLL
DalDro bound to the terminating Escherichia coli 70S ribosome
DalDroS bound to the Escherichia coli 50S ribosomal subunit
Staphylococcus aureus 50S ribosome in complex with RRF, EF-G and fusidic acid (50S-RRF-EF-G-FA)
SM: FUA GDP
Staphylococcus aureus 70S ribosome in complex with RRF, EF-G and fusidic acid (70S-RRF-EF-G-FA)
Ternary complex of E. coli leucyl-tRNA synthetase mutant W177A, tRNA(leu) and the leucyl adenylate analog LeuAMS in the aminoacyl transfer state
SM: LSS LSS
Ternary complex of E. coli leucyl-tRNA synthetase mutant R178A, tRNA(leu) and the leucyl adenylate analog LeuAMS in the aminoacyl transfer state
E. coli 70S ribosome with A- and P-site tRNA
SM: SCM
E. coli 70S ribosome with A/P- and P/E-site tRNA
E. coli 70S ribosome, trapped conformational ground state of SSU-h44 apical loop, with A- and P-site tRNA
70S Coxiella burnetii Ribosome with Doxycycline and HPFcold
INTERACTION BETWEEN A FLUOROQUINOLONE DERIVATIVE AND RNAS WITH A SINGLE BULGE
SM: 53D
SARS-CoV-2 E-RTC in complex with RNA-nsp9 and GMPPNP
SM: GNP
Current selection range: to
Filter entries " Experimental resolution " between the two values. Global DB range: 0.6 – 11.2
Filter entries " Molecular weight (compound) " between the two values. Global DB range: 150 – 1000
Filter entries " Deposition date " between the two values. Global DB range: 1986 – 2027
Filter entries " Molecular weight (complex) " between the two values. Global DB range: 0 – 13090
Filter entries " Number of atoms " between the two values. Global DB range: 5 – 70
Filter entries " Number of interacting chains " between the two values. Global DB range: 1 – 4
Filter entries " Pocket size " between the two values. Global DB range: 15.9 – 394.0
Filter entries " SiteScore " between the two values. Global DB range: 0.3 – 1.3
Filter entries " Dscore " between the two values. Global DB range: -0.1 – 1.4
Filter entries " Exposure " between the two values. Global DB range: 0.1 – 1.0
Filter entries " Enclosure " between the two values. Global DB range: 0.3 – 1.0
Filter entries " Hydrophobicity " between the two values. Global DB range: 0.0 – 3.1
Filter entries " Hydrophilicity " between the two values. Global DB range: 0.2 – 2.8
Filter entries " Donor/Acceptor " between the two values. Global DB range: 0.0 – 5.0
Filter entries " Volume " between the two values. Global DB range: 21.2 – 1528.8