Harnessing RIBOnucleic acid - Small molecules Structures
Manikomycin bound to the Escherichia coli 70S ribosome
SM: PAR
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and RBFA (Outward conformation) (State M3)
SM: NAD SPM
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15, RBFA, and mtIF2 (State M2.1)
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and RBFA (Inward conformation) (State M2)
Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15 and mS37 (State M4)
SM: NAD
Structure of the ZAK-bound human disome
SM: ANM
Structure of the 70S-EF-G(P610L)-GDP-Pi ribosome complex with tRNAs in hybrid state 1 (H1-EF-G(P610L)-GDP-Pi)
SM: AM2 GDP
Structure of the 70S-EF-G(P610L)-GDP-Pi ribosome complex with tRNAs in hybrid state 2 (H2-EF-G(P610L)-GDP-Pi)
Human mitoribosome bound to TACO1 (Translational activator of COX1), mRNA, A/A-, P/P- and (partial) E/E-tRNAs
WT-HEK 80S ribosome bound to Kozak mRNA (WT-Kozak)
SM: HYG
WT-HEK 80S ribosome bound to TISU mRNA (WT-TISU)
RPS26dC HEK mutant 80S ribosome bound to Kozak mRNA (RPS26dC-Kozak)
SM: ANM HYG
WT-HEK 80S ribosome bound to H2B mRNA (WT-H2B)
Structure of Yeast RNA polymerase II elongation complex with ATP frame-7
SM: ATP
Structure of Yeast RNA polymerase II elongation complex with ATP frame-8
Structure of Yeast RNA polymerase II elongation complex with ATP frame-9
Structure of Yeast RNA polymerase II elongation complex with ATP frame-10
Structure of Yeast RNA polymerase II elongation complex with ATP frame-11
Structure of Yeast RNA polymerase II elongation complex with ATP frame-12
Structure of Yeast RNA polymerase II elongation complex with ATP frame-13
Structure of Yeast RNA polymerase II elongation complex with ATP frame-14
Structure of Yeast RNA polymerase II elongation complex with ATP frame-15
Structure of Yeast RNA polymerase II elongation complex with ATP frame-16
Structure of Yeast RNA polymerase II elongation complex with ATP frame-17
Structure of Yeast RNA polymerase II elongation complex with ATP frame-18
Structure of Yeast RNA polymerase II elongation complex with ATP frame-19
Structure of Yeast RNA polymerase II elongation complex with ATP frame-20
Structure at 1.9 A resolution of Thermus thermophilus tyrosyl-tRNA synthetase bound to wild-type modified tRNA(Tyr), tyrosine and AMP
SM: 1PE
Structure at 1.9 A resolution of Thermus thermophilus tyrosyl-tRNA synthetase bound to wild-type tRNATyr(GUC).
Cryo-EM structure of the catalytic core of human telomerase at the initiation state of the repeat addition cycle
SM: 1GC
Cryo-EM structure of the catalytic core of human telomerase at the elongation state of the repeat addition cycle
SM: A1ACD
Cryo-EM structure of the catalytic core of human telomerase at the pre-termination state of the repeat addition cycle
Doxycycline Bound E. coli Ribosome with Rearranged Peptidyl Transferase Centre
SM: DXT
CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING N1-METHYLPSEUDOURIDINE
CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING URIDINE
Cryo-EM structure of SKM-70S ribosomal stalled complex in the rotated state with hybrid tRNAs
SM: A1JAI
CryoEM structure of transcribing RNA polymerase II elongation complex with ATP and Elf1
30S Doxycycline Bound E. coli Ribosome
Structure of a stalled E. coli 70S RNC-NuoK-70 in complex with the membrane protein insertase SecYEG-YidC
SM: SPM
Doxycycline Bound C. burnetii 30S Ribosome
Cryo-EM structure of the 70S ribosome from Francisella tularensis bound to antibiotics chloramphenicol and gentamicin
SM: CLM LLL
DalDro bound to the terminating Escherichia coli 70S ribosome
DalDroS bound to the Escherichia coli 50S ribosomal subunit
Staphylococcus aureus 50S ribosome in complex with RRF, EF-G and fusidic acid (50S-RRF-EF-G-FA)
SM: FUA GDP
Staphylococcus aureus 70S ribosome in complex with RRF, EF-G and fusidic acid (70S-RRF-EF-G-FA)
E. coli 70S ribosome with A- and P-site tRNA
SM: SCM
E. coli 70S ribosome with A/P- and P/E-site tRNA
E. coli 70S ribosome, trapped conformational ground state of SSU-h44 apical loop, with A- and P-site tRNA
Triple Stack Doxycycline Bound 50S Subunit of the Coxiella burnetii Ribosome
70S Coxiella burnetii Ribosome with Doxycycline and HPFcold
INTERACTION BETWEEN A FLUOROQUINOLONE DERIVATIVE AND RNAS WITH A SINGLE BULGE
SM: 53D
SARS-CoV-2 E-RTC in complex with RNA-nsp9 and GMPPNP
SM: GNP
CryoEM structure of the T.thermophilus transcription initiation complex bound to Gp4A-C-U and CTP, -1 dC in the template DNA strand
SM: CTP
Crystal structure of 2'-dG-III riboswitch with Guanosine, manganese saok
SM: GMP
human mitoribosome trapped by retapamulin
SM: G34 NAD
Cryo- EM structure of 75S ribosome with A/P- & P/E- tRNAs from Entamoeba histolytica bound to antibiotic paromomycin
Cryo- EM structure of small subunit (body) of 75S ribosome with A/P- & P/E- tRNAs from Entamoeba histolytica bound to antibiotic paromomycin
Crystal structure of Guanine-II riboswitch in complex with 7,8-dihydroneopterin
SM: NPR
Crystal structure of Guanine-II riboswitch in complex with isoxanthopterin
SM: 7PD
Current selection range: to