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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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2077 RNA-SM complexes found
Structure of complex 8wax

8wax

De novo transcribing complex 14 (TC14), the early elongation complex with Pol II positioned 14nt downstream of TSS

SM: W0F

Structure of complex 8way

8way

De novo transcribing complex 15 (TC15), the early elongation complex with Pol II positioned 15nt downstream of TSS

SM: W0F

Structure of complex 8waz

8waz

De novo transcribing complex 16 (TC16), the early elongation complex with Pol II positioned 16nt downstream of TSS

SM: W0F

Structure of complex 8wb0

8wb0

De novo transcribing complex 17 (TC17), the early elongation complex with Pol II positioned 17nt downstream of TSS

SM: W0F

Structure of complex 8xko

8xko

CryoEM structure of compound HNC-1664 bound with RdRP-RNA complex of SARS-CoV-2

SM: A1LVZ

Structure of complex 8xpo

8xpo

Cryo-EM structure of Lassa virus RdRP elongation complex with the NTP form of compound HNC-1664 bound in the active site

SM: A1LVZ

Structure of complex 8xsx

8xsx

Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2

SM: T1C T1C T1C T1C T1C T1C T1C

Structure of complex 8xsy

8xsy

Cryo-EM structure of the human 80S ribosome with Tigecycline, e-tRNA and CCDC124 (40S head Swivelled)

SM: T1C T1C T1C T1C T1C T1C T1C T1C

Structure of complex 8xsz

8xsz

Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA

SM: T1C T1C T1C T1C T1C

Structure of complex 8xze

8xze

Crystal structure of THF-II riboswitch with THF and soaked with Ir

SM: SPM THG

Structure of complex 8xzl

8xzl

Crystal structure of folE riboswitch with DHF

SM: DHF SPM

Structure of complex 8xzm

8xzm

Crystal structure of folE riboswitch with DHN

SM: NPR SPM

Structure of complex 8xt0

8xt0

Cryo-EM structure of the human 55S mitoribosome with 5um Tigecycline

SM: T1C T1C T1C

Structure of complex 8xt1

8xt1

Cryo-EM structure of the human 39S mitoribosome with 5uM Tigecycline

SM: T1C

Structure of complex 8xt2

8xt2

Cryo-EM structure of the human 55S mitoribosome with 10uM Tigecycline

SM: T1C T1C T1C

Structure of complex 8xt3

8xt3

Cryo-EM structure of the human 39S mitoribosome with 10uM Tigecycline

SM: T1C

Structure of complex 8xz3

8xz3

Mycobacterium smegmatis 50S ribosomal subunit with Erythromycin

SM: ERY

Structure of complex 8xzn

8xzn

Crystal structure of folE riboswitch with BH4

SM: H4B SPM

Structure of complex 8xzo

8xzo

Crystal structure of folE riboswitch with Guanine

SM: SPM

Structure of complex 8xzp

8xzp

Crystal structure of folE riboswitch with 8-CH3 Guanine

SM: A1LXN SPM

Structure of complex 8xzq

8xzq

Crystal structure of folE riboswitch with 8-N Guanine

SM: SPM

Structure of complex 8xzr

8xzr

Crystal structure of folE riboswitch with 8-NH2 Guanine

SM: ANG SPM

Structure of complex 8xzw

8xzw

Crystal structure of THF-II riboswitch with THF and soaked with Ir

SM: SPM THG

Structure of complex 8y2o

8y2o

The Cryo-EM structure of human tRNA methyltransferase FTSJ1-THADA with substrate tRNA and S-adenosyl homocysteine (SAH)

SM: SAH

Structure of complex 8y36

8y36

cryo-EM structure of Staphylococcus aureus(ATCC 29213) 50S ribosome in complex with MCX-190.

SM: A1D6G

Structure of complex 8y37

8y37

Cryo-EM structure of Staphylococcus aureus (15B196) 50S ribosome in complex with MCX-190.

SM: A1D6G

Structure of complex 8y38

8y38

Cryo-EM structure of Staphylococcus aureus 70S ribosome (strain 15B196) in complex with MCX-190.

SM: A1D6G

Structure of complex 8y39

8y39

cryo-EM structure of Staphylococcus aureus(ATCC 29213) 70S ribosome in complex with MCX-190.

SM: A1D6G

Structure of complex 8y5k

8y5k

E.coli transcription translation coupling complex in TTC-A state 2 containing mRNA with 27-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and viomycin

SM: GDP

Structure of complex 8y5m

8y5m

E.coli transcription translation coupling complex in TTC-B state 2 containing mRNA with 27-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and viomycin

SM: GDP

Structure of complex 8y5n

8y5n

E.coli transcription translation coupling complex in TTC-A state 3 containing mRNA with 21-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and viomycin

SM: GDP

Structure of complex 8y5o

8y5o

E.coli transcription translation coupling complex in TTC-B state 3 (subclass1) containing mRNA with 30-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and viomycin

SM: GDP

Structure of complex 8y5p

8y5p

E.coli transcription translation coupling complex in TTC-B state 4 (subclass 1) containing mRNA with 24-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and viomycin

SM: GDP

Structure of complex 8y5q

8y5q

E.coli transcription translation coupling complex in TTC-B state 4 (subclass 2) containing mRNA with 27-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and GDPCP

SM: GCP

Structure of complex 8y5r

8y5r

E.coli Transcription translation coupling complex in TTC-B state 5 (subclass 1) containing mRNA with 27-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and fusidic acid

SM: FUA

Structure of complex 8y5t

8y5t

E.coli Transcription translation coupling complex in TTC-B state 5 (subclass 3) containing mRNA with 27-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and fusidic acid

SM: FUA

Structure of complex 8yam

8yam

Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound

SM: A1LYK

Structure of complex 8yan

8yan

Crystal structure of a class I PreQ1 riboswitch complexed with a synthetic compound

SM: A1LYL

Structure of complex 8ydg

8ydg

E.coli transcription translation coupling complex in TTC-B state 3 (subclass2) containing mRNA with 39-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and viomycin

SM: GDP

Structure of complex 8ydj

8ydj

E.coli transcription translation coupling complex in TTC-P containing mRNA with 39-mer spacer, NusG, NusA, fMet-tRNA(iMet), Phe-tRNA(Phe), and viomycin

SM: GDP

Structure of complex 8yno

8yno

RNA duplex containing Formamide

SM: SPM

Structure of complex 8yoo

8yoo

Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline

SM: T1C T1C T1C T1C T1C T1C

Structure of complex 8z8x

8z8x

Cryo-EM structure of Thogoto virus polymerase in a transcription initiation conformation

SM: G2P

Structure of complex 8z90

8z90

Cryo-EM structure of Thogoto virus polymerase in transcription initiation conformation 2

SM: G2P

Structure of complex 8znq

8znq

Solution structure of the complex of naphthyridine-azaquinolone and an RNA with ACG/AUA motif

SM: NAZ

Structure of complex 9avr

9avr

Human eIF4A-1 in complex with AMP-PNP, RNA, and the inhibitor silvestrol

SM: A1AG8

Structure of complex 9b00

9b00

Crystal structure of the wild-type Thermus thermophilus 70S ribosome in complex with berberine analog of chloramphenicol CAM-BER, mRNA, deacylated A- and E-site tRNAphe, and deacylated P-site tRNAmet at 2.80A resolution

SM: A1AIX A1AIX

Structure of complex 9b4z

9b4z

E. coli 70S ribosome complex (N1-methylated 16S A1408 + arbekacin)

SM: 84G 84G

Structure of complex 9b50

9b50

E. coli 70S ribosome complex (unmethylated 16S A1408 + arbekacin)

SM: 84G 84G

Structure of complex 9b51

9b51

E. coli 70S ribosome complex (N1-methylated 16S A1408 + G418)

SM: GET GET

Structure of complex 9bdd

9bdd

Cryo-EM Structure of Non-Cognate Substrate Bound in the Entry Site (ES) of Human Mitochondrial Transcription Elongation Complex

SM: APC

Structure of complex 9bh5

9bh5

High-resolution C. elegans 80S ribosome structure - class 1

SM: 3HE

Structure of complex 9blf

9blf

SARS-CoV-2 core polymerase complex inhibited by araCTP

SM: HF4

Structure of complex 9bs0

9bs0

YphC-treated 45SYphC particle. Class 5

SM: GNP

Structure of complex 9bun

9bun

RhoBAST aptamer RNA in complex with 5(6)-carboxytetramethylrhodamine

SM: FH8 FH8 FH8 FH8

Structure of complex 9bzc

9bzc

Cocrystal structure of Clostridium beijerinckii ZTP riboswitch with ZMP and Cs

SM: AMZ

Structure of complex 9c0j

9c0j

Structure of the elongating DRT2 reverse transcriptase in complex with its non-coding RNA and dNTPs

SM: TTP

Structure of complex 9c4g

9c4g

Cutibacterium acnes 50S ribosomal subunit with Clindamycin bound

SM: CLY

Structure of complex 9c6k

9c6k

Cryo-EM structure of the TPP riboswitch embedded in an RNA scaffold bound to thiamine pyrophosphate

SM: TPP

Structure of complex 9cai

9cai

High-resolution C. elegans 80S ribosome structure - class 1

SM: 3HE