Complex 4e8t
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.34 |
| System mass | 133.50 kDa |
| Deposition year | 2012 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | Oceanobacillus |
| RCSB PDB Entry | 4e8t |
| Reference | Marcia Marco, Pyle Anna Marie. 2012. Visualizing Group II Intron Catalysis through the Stages of Splicing Cell |
| Equivalence Class |
NR_all_35054.12
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | EPE |
| Residue | . / 442 |
| Chain | RA / A |
| Non-redundant | False |
| Interacting RNA chains | A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: ribozyme |
| RNA family global | ribozyme |
| Volume | - |
| Hydrophobicity | - |
| Hydrophilicity | - |
| Buriedness | - |
| Don/acc character | - |
| SiteScore | - |
| D Score | - |
| Kd | — |
| Compound | EPE |
| Residue | . / 444 |
| Chain | TA / A |
| Non-redundant | False |
| Interacting RNA chains | A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: ribozyme |
| RNA family global | ribozyme |
| Volume | - |
| Hydrophobicity | - |
| Hydrophilicity | - |
| Buriedness | - |
| Don/acc character | - |
| SiteScore | - |
| D Score | - |
| Kd | — |
| Compound | EPE |
| Residue | . / 445 |
| Chain | UA / A |
| Non-redundant | False |
| Interacting RNA chains | A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: ribozyme |
| RNA family global | ribozyme |
| Volume | 161.21 Å3 |
| Hydrophobicity | 0.010 |
| Hydrophilicity | 1.235 |
| Buriedness | 0.671 |
| Don/acc character | 1.823 |
| SiteScore | 0.807 |
| D Score | 0.523 |
| Kd | — |
| Compound | EPE |
| Residue | . / 446 |
| Chain | VA / A |
| Non-redundant | False |
| Interacting RNA chains | A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: ribozyme |
| RNA family global | ribozyme |
| Volume | 134.80 Å3 |
| Hydrophobicity | 0.013 |
| Hydrophilicity | 0.824 |
| Buriedness | 0.509 |
| Don/acc character | 3.115 |
| SiteScore | 1.065 |
| D Score | 0.977 |
| Kd | — |
| Compound | EPE |
| Residue | . / 447 |
| Chain | WA / A |
| Non-redundant | False |
| Interacting RNA chains | A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: ribozyme |
| RNA family global | ribozyme |
| Volume | 70.66 Å3 |
| Hydrophobicity | 0.000 |
| Hydrophilicity | 0.665 |
| Buriedness | 0.453 |
| Don/acc character | 3.215 |
| SiteScore | 0.934 |
| D Score | 0.836 |
| Kd | — |
| Compound | SPM |
| Residue | . / 440 |
| Chain | PA / A |
| Non-redundant | False |
| Interacting RNA chains | A/A |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | A/A: ribozyme |
| RNA family global | ribozyme |
| Volume | 236.33 Å3 |
| Hydrophobicity | 0.249 |
| Hydrophilicity | 0.856 |
| Buriedness | 0.654 |
| Don/acc character | 0.966 |
| SiteScore | 0.818 |
| D Score | 0.620 |
| Kd | — |
| Compound | SPM |
| Residue | . / 441 |
| Chain | QA / A |
| Non-redundant | False |
| Interacting RNA chains | A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: ribozyme |
| RNA family global | ribozyme |
| Volume | 228.44 Å3 |
| Hydrophobicity | 0.129 |
| Hydrophilicity | 0.959 |
| Buriedness | 0.647 |
| Don/acc character | 2.779 |
| SiteScore | 0.879 |
| D Score | 0.692 |
| Kd | — |