Complex 4pjo
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.30 |
| System mass | 453.82 kDa |
| Deposition year | 2014 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 4pjo |
| Reference | Kondo Yasushi, Oubridge Chris, van Roon Anne-Marie M, Nagai Kiyoshi. 2015. Crystal structure of human U1 snRNP, a small nuclear ribonucleoprotein particle, reveals the mechanism of 5′ splice site recognition eLife |
| Equivalence Class |
NR_all_72137.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | EPE |
| Residue | . / 201 |
| Chain | TA / 1 |
| Non-redundant | True |
| Interacting RNA chains | J/1 |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | J/1: TAR_rna |
| RNA family global | TAR_rna |
| Volume | 438.70 Å3 |
| Hydrophobicity | 0.074 |
| Hydrophilicity | 1.042 |
| Buriedness | 0.686 |
| Don/acc character | 1.698 |
| SiteScore | 0.728 |
| D Score | 0.674 |
| Kd | — |
| Compound | EPE |
| Residue | . / 201 |
| Chain | HB / 2 |
| Non-redundant | True |
| Interacting RNA chains | U/2 |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | U/2: TAR_rna |
| RNA family global | TAR_rna |
| Volume | 518.27 Å3 |
| Hydrophobicity | 0.094 |
| Hydrophilicity | 1.466 |
| Buriedness | 0.720 |
| Don/acc character | 0.935 |
| SiteScore | 1.027 |
| D Score | 0.718 |
| Kd | — |