Harnessing RIBOnucleic acid - Small molecules Structures
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Cryo-EM structure of the catalytic core of human telomerase at the pre-termination state of the repeat addition cycle
SM: 1GC
Doxycycline Bound E. coli Ribosome with Rearranged Peptidyl Transferase Centre
SM: DXT
CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING N1-METHYLPSEUDOURIDINE
SM: HYG
CRYO-EM STRUCTURE OF HUMAN 80S RIBOSOME WITH A/P/E-SITE TRNA AND MRNA CONTAINING URIDINE
Cryo-EM structure of SKM-70S ribosomal stalled complex in the rotated state with hybrid tRNAs
SM: A1JAI
CryoEM structure of Candida auris 80S ribosome in complex with Cycloheximide and Geneticin G418
SM: 3HE GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET GET
30S Doxycycline Bound E. coli Ribosome
Structure of a stalled E. coli 70S RNC-NuoK-70 in complex with the membrane protein insertase SecYEG-YidC
SM: SPM
Doxycycline Bound C. burnetii 30S Ribosome
Cryo-EM structure of the 70S ribosome from Francisella tularensis bound to antibiotics chloramphenicol and gentamicin
SM: CLM LLL LLL LLL LLL LLL LLL LLL LLL LLL
CryoEM structure of Candida auris 80S ribosome in complex with Blasticidin S
SM: BLS
DalDro bound to the terminating Escherichia coli 70S ribosome
DalDroS bound to the Escherichia coli 50S ribosomal subunit
Staphylococcus aureus 50S ribosome in complex with RRF, EF-G and fusidic acid (50S-RRF-EF-G-FA)
SM: FUA GDP
Staphylococcus aureus 70S ribosome in complex with RRF, EF-G and fusidic acid (70S-RRF-EF-G-FA)
Ternary complex of E. coli leucyl-tRNA synthetase mutant W177A, tRNA(leu) and the leucyl adenylate analog LeuAMS in the aminoacyl transfer state
SM: LSS LSS
Ternary complex of E. coli leucyl-tRNA synthetase mutant R178A, tRNA(leu) and the leucyl adenylate analog LeuAMS in the aminoacyl transfer state
E. coli 70S ribosome with A- and P-site tRNA
SM: SCM
E. coli 70S ribosome with A/P- and P/E-site tRNA
E. coli 70S ribosome, trapped conformational ground state of SSU-h44 apical loop, with A- and P-site tRNA
Triple Stack Doxycycline Bound 50S Subunit of the Coxiella burnetii Ribosome
SM: DXT DXT DXT
70S Coxiella burnetii Ribosome with Doxycycline and HPFcold
INTERACTION BETWEEN A FLUOROQUINOLONE DERIVATIVE AND RNAS WITH A SINGLE BULGE
SM: 53D
SARS-CoV-2 E-RTC in complex with RNA-nsp9 and GMPPNP
SM: GNP
CryoEM structure of the T.thermophilus transcription initiation complex bound to Gp4A-C-U and CTP, -1 dC in the template DNA strand
SM: CTP
Crystal structure of 2'-dG-III riboswitch with Guanosine, manganese saok
SM: GMP
human mitoribosome trapped by retapamulin
SM: G34 NAD
Cryo- EM structure of 75S ribosome with A/P- & P/E- tRNAs from Entamoeba histolytica bound to antibiotic paromomycin
SM: PAR
Cryo- EM structure of small subunit (body) of 75S ribosome with A/P- & P/E- tRNAs from Entamoeba histolytica bound to antibiotic paromomycin
Crystal structure of Guanine-II riboswitch in complex with 7,8-dihydroneopterin
SM: NPR
Crystal structure of Guanine-II riboswitch in complex with isoxanthopterin
SM: 7PD
Crystal structure of Guanine-II riboswitch in complex with 8-aminoguanine
SM: ANG ANG
Crystal structure of Guanine-II riboswitch in complex with 8-oxoguanine
SM: OXG
Crystal structure of Guanine-II riboswitch in complex with 8-methylguanine
SM: A1LXN
Crystal structure of Guanine-II riboswitch in complex with tetrahydrobiopterin
SM: H4B
Cryo-EM structures of the Azoarcus pre-tRNA(ILE) conformation a undergoing the first-step self-splicing
Cryo-EM structures of the Azoarcus pre-tRNA(ILE) conformation b undergoing the first-step self-splicing
Cryo-EM structure of substrate-bound DRT9 hexamer complex
SM: DTP
Crystal structure of Broccoli aptamer in with BI
SM: A1EST
Human mitoribosome in a non-rotated state, with multiple neomycin molecules bound, featuring A/A-site and P/P-site tRNAs
SM: NAD NMY NMY NMY NMY NMY NMY NMY NMY SPM
Human cytosolic ribosome in a rotated state, with multiple neomycin molecules bound, featuring A/P-site and P/E-site tRNAs
SM: NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY NMY
Crimean-Congo hemorrhagic fever virus RNA polymerase containing a 10-bp RNA product and incorporated 2FC
SM: 2KH
Crimean-Congo hemorrhagic fever virus RNA polymerase containing a 10-bp RNA product and incorporated cytidine
Crimean-Congo hemorrhagic fever virus RNA polymerase containing a 15-bp RNA product
Crimean-Congo hemorrhagic fever virus RNA polymerase containing a 9-bp RNA product
RNA primer non-enzymatic extension product with RNA substrate
SM: EQ4 EQ4
RNA primer non-enzymatic extension product with DNA substrate
SM: A1CWA A1CWA
De novo initial transcribing RNA polymerase with 2-mer RNA and bound CTP / Michaelis complex (RPitc2+CTP)
Cryo-EM structure of Escherichia coli transcription initiation complex with GpA and pseudouridimycin (PUM)
SM: PUM
Cryo-EM structure of Escherichia coli transcription initiation complex with GpA and des-hydroxy pseudouridimycin (des-hydroxy PUM)
SM: A1CYH
CryoEM structure of human NSUN2(C271A) with SAH cross-linked to tRNA Lys(CTT) (D-arm conformation)
SM: SAH
CryoEM structure of human NSUN2(C271A) with SAH cross-linked to tRNA Lys(CTT) (No D-arm conformation)
CryoEM structure of human NSUN2 with tRNA Lys(CTT) and SFG (D-arm conformation)
SM: SFG
CryoEM structure of human NSUN2 with tRNA Lys(CTT) and SFG (No D-arm conformation)
CryoEM structure of human NSUN2(C271A) with SAH cross-linked to tRNA Lys(TTT) (D-arm conformation)
CryoEM structure of human NSUN2(C271A) with SAH cross-linked to tRNA Lys(TTT) (No D-arm conformation)
CryoEM structure of human NSUN2(C271A) with SAH cross-linked to a pre-tRNA Leu(CAA) intron
Current selection range: to
Filter entries " Experimental resolution " between the two values. Global DB range: 0.6 – 11.2
Filter entries " Molecular weight (compound) " between the two values. Global DB range: 150 – 1000
Filter entries " Deposition date " between the two values. Global DB range: 1986 – 2027
Filter entries " Molecular weight (complex) " between the two values. Global DB range: 0 – 13090
Filter entries " Number of atoms " between the two values. Global DB range: 5 – 70
Filter entries " Number of interacting chains " between the two values. Global DB range: 1 – 4
Filter entries " Pocket size " between the two values. Global DB range: 15.9 – 394.0
Filter entries " SiteScore " between the two values. Global DB range: 0.3 – 1.3
Filter entries " Dscore " between the two values. Global DB range: -0.1 – 1.4
Filter entries " Exposure " between the two values. Global DB range: 0.1 – 1.0
Filter entries " Enclosure " between the two values. Global DB range: 0.3 – 1.0
Filter entries " Hydrophobicity " between the two values. Global DB range: 0.0 – 3.1
Filter entries " Hydrophilicity " between the two values. Global DB range: 0.2 – 2.8
Filter entries " Donor/Acceptor " between the two values. Global DB range: 0.0 – 5.0
Filter entries " Volume " between the two values. Global DB range: 21.2 – 1528.8