Harnessing RIBOnucleic acid - Small molecules Structures
X-ray crystal structure of a bacterial reiterative transcription complex of pyrBI promoter
SM: UTP
Cryo-EM structure of E. coli RNA polymerase elongation complex bound to CTP substrate
SM: CTP
Telomerase Reverse Transcriptase ternary complex, TERT:DNA:dGpCpp
SM: G2P
E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching GTP ("Fresh" crystal soaked with GTP for 1 hour)
SM: GTP
E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Fresh" crystal soaked with CTP, GTP, and ddTTP for 30 minutes)
E. coli sigma-S transcription initiation complex with 3-nt RNA ("Old" crystal soaked with GTP and ATP for 30 minutes)
E. coli sigma-S transcription initiation complex with a 3-nt RNA ("old" crystal soaked with GTP and dinucleotide GpA for 30 minutes)
E. coli sigma-S transcription initiation complex with a 4-nt RNA and a UTP ("Old" crystal soaked with UTP, ddCTP, and dinucleotide ApG for 30 minutes)
E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching ATP ("Fresh" crystal soaked with ATP for 2 hours)
SM: ATP
Thermus thermophilus RNA polymerase initially transcribing complex with 2'dCTP
SM: DCP
Thermus thermophilus RNA polymerase initially transcribing complex with 3'dCTP
SM: CH1
Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex
SM: P5E
Thermus thermophilus RNA polymerase transcription initiation complex containing a template-strand purine at position TSS-2, UpA RNA primer and CMPcPP
SM: 2TM
Thermus thermophilus transcription initiation complex containing a template-strand purine at position TSS-2, GpG RNA primer, and CMPcPP
GsI-IIC RT Template-Switching Complex (twinned)
SM: DTP
Ternary complex of TERT (telomerase reverse transcriptase) with RNA template, DNA primer, an incoming dGTP and a downstream hybrid duplex
SM: DGT
Human DNA Pol eta with rA-ended primer and dAMPNPP
SM: DZ4
Human DNA Pol eta S113A with rA-ended primer and dAMPNPP
Human DNA Pol eta S113A with rA-ended primer and dATP: in crystallo reaction for 0 s
Escherichia coli RNA polymerase and RapA elongation complex
Escherichia coli RNA polymerase elongation complex
Crystal structure of DNA polymerase alpha catalytic core in complex with dCTP and template/primer having T-C mismatch at the post-insertion site
Structure of the pre state human RNA Polymerase I Elongation Complex
QDE-1 in complex with DNA template, RNA primer and 3'-dGTP
QDE-1 in complex with DNA template, RNA primer and AMPNPP
SM: ZAN
QDE-1 in complex with 12nt DNA template, ATP and 3'-dGTP
Long Interspersed Nuclear Element 1 (LINE-1) reverse transcriptase ternary complex with hybrid duplex and dTTP
SM: TTP
T7 RNA polymerase elongation complex with unnatural base dPa-DsTP pair
SM: S96
T7 RNA polymerase elongation complex with unnatural base dPa-ATP mismatch
Human DNA polymerase eta-DNA-rG-ended primer-dGMPNPP ternary mismatch complex with Mn2+
SM: XG4
Human DNA polymerase eta-DNA-rC-ended primer-dGMPNPP ternary mismatch complex with Mn2+
Human DNA polymerase eta-DNA-rA-ended primer-dGMPNPP ternary mismatch complex with Mg2+
Human DNA polymerase eta-DNA-rU-ended primer-dGMPNPP ternary mismatch complex with Mg2+
Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:ground state at pH7.0 (K+ MES) with 1 Ca2+ ion
Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 30s
Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 60s
Human DNA polymerase eta-DNA-rG-ended primer-dGMPNPP ternary mismatch complex with Mg2+
Human DNA polymerase eta-DNA-rC-ended primer-dGMPNPP ternary mismatch complex with Mg2+
M. tuberculosis RNAP pause escaped complex with Bacillus subtilis NusG and GMPCPP
M. tuberculosis RNAP elongation complex with NusG and CMPCPP
M. tuberculosis RNAP paused complex with B. subtilis NusG and GMPCPP
DNA initiation subcomplex of Xenopus laevis DNA polymerase alpha-primase
Bombyx mori R2 retrotransposon initiating target-primed reverse transcription
Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc
Structure of LINE-1 ORF2p with template:primer hybrid
E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dS-BTP base pair in the active site
SM: X0F
E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-UTP base pair in the active site
SM: DGP UTP
E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-STP base pair in the active site
SM: X0O
E. coli DNA-directed RNA polymerase transcription elongation complex bound to the unnatural dZ-PTP base pair in the active site
SM: S9F
Cryo-EM Structure of Cognate Substrate ATP Bound in the Entry Site (ES) of Human Mitochondrial Transcription Elongation Complex
SM: APC
Cryo-EM structure of Substrate ATP Bound in the Insertion Site (IS) of Human Mitochondrial Transcription Elongation Complex
STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION USING A FREE-ELECTRON LASER
STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION AT 3.0 A OF T834P MUTANT USING A FREE-ELECTRON LASER
RNA polymerase II elongation complex with Fapy-dG lesion soaking with CTP before chemistry
Cyanobacterial RNA polymerase elongation complex with NusG and CTP
Human LINE-1 retrotransposon ORF2 protein engaged with template RNA in elongation state
DNA initiation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase
DNA initiation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase
Thermus thermophilus initiation transcription complex containing CMPcPP in the post-translocated state
Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II positioned 2nt downstream of TSS.
SM: W0F
Current selection range: to
