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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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206 RNA-SM complexes found
Structure of complex 6p1s

6p1s

Post-catalytic nicked complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and newly incorporated AMP

SM: ATP

Structure of complex 6p71

6p71

X-ray crystal structure of a bacterial reiterative transcription complex of pyrBI promoter

SM: UTP

Structure of complex 6rh3

6rh3

Cryo-EM structure of E. coli RNA polymerase elongation complex bound to CTP substrate

SM: CTP

Structure of complex 6usr

6usr

Telomerase Reverse Transcriptase ternary complex, TERT:DNA:dGpCpp

SM: G2P

Structure of complex 6uu0

6uu0

E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching GTP ("Fresh" crystal soaked with GTP for 1 hour)

SM: GTP

Structure of complex 6uu1

6uu1

E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Fresh" crystal soaked with CTP, GTP, and ddTTP for 30 minutes)

SM: CTP

Structure of complex 6uu2

6uu2

E. coli sigma-S transcription initiation complex with 3-nt RNA ("Old" crystal soaked with GTP and ATP for 30 minutes)

SM: GTP

Structure of complex 6uu4

6uu4

E. coli sigma-S transcription initiation complex with a 3-nt RNA ("old" crystal soaked with GTP and dinucleotide GpA for 30 minutes)

SM: GTP

Structure of complex 6uu6

6uu6

E. coli sigma-S transcription initiation complex with a 4-nt RNA and a UTP ("Old" crystal soaked with UTP, ddCTP, and dinucleotide ApG for 30 minutes)

SM: UTP

Structure of complex 6uuc

6uuc

E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching ATP ("Fresh" crystal soaked with ATP for 2 hours)

SM: ATP

Structure of complex 6wox

6wox

Thermus thermophilus RNA polymerase initially transcribing complex with 2'dCTP

SM: DCP

Structure of complex 6woy

6woy

Thermus thermophilus RNA polymerase initially transcribing complex with 3'dCTP

SM: CH1

Structure of complex 6ymw

6ymw

Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex

SM: P5E

Structure of complex 7eh0

7eh0

Thermus thermophilus RNA polymerase transcription initiation complex containing a template-strand purine at position TSS-2, UpA RNA primer and CMPcPP

SM: 2TM

Structure of complex 7eh1

7eh1

Thermus thermophilus transcription initiation complex containing a template-strand purine at position TSS-2, GpG RNA primer, and CMPcPP

SM: 2TM

Structure of complex 7k9y

7k9y

GsI-IIC RT Template-Switching Complex (twinned)

SM: DTP DTP

Structure of complex 7kqn

7kqn

Ternary complex of TERT (telomerase reverse transcriptase) with RNA template, DNA primer, an incoming dGTP and a downstream hybrid duplex

SM: DGT DGT

Structure of complex 7m7m

7m7m

Human DNA Pol eta with rA-ended primer and dAMPNPP

SM: DZ4

Structure of complex 7m7r

7m7r

Human DNA Pol eta S113A with rA-ended primer and dAMPNPP

SM: DZ4

Structure of complex 7m89

7m89

Human DNA Pol eta S113A with rA-ended primer and dATP: in crystallo reaction for 0 s

SM: DTP

Structure of complex 7mkn

7mkn

Escherichia coli RNA polymerase and RapA elongation complex

SM: 2TM

Structure of complex 7mko

7mko

Escherichia coli RNA polymerase elongation complex

SM: 2TM

Structure of complex 7n2m

7n2m

Crystal structure of DNA polymerase alpha catalytic core in complex with dCTP and template/primer having T-C mismatch at the post-insertion site

SM: DCP

Structure of complex 7vba

7vba

Structure of the pre state human RNA Polymerase I Elongation Complex

SM: 2TM

Structure of complex 7y7r

7y7r

QDE-1 in complex with DNA template, RNA primer and 3'-dGTP

SM: GTP GTP

Structure of complex 7y7s

7y7s

QDE-1 in complex with DNA template, RNA primer and AMPNPP

SM: ZAN ZAN

Structure of complex 7y7t

7y7t

QDE-1 in complex with 12nt DNA template, ATP and 3'-dGTP

SM: GTP

Structure of complex 8c8j

8c8j

Long Interspersed Nuclear Element 1 (LINE-1) reverse transcriptase ternary complex with hybrid duplex and dTTP

SM: TTP

Structure of complex 8dh4

8dh4

T7 RNA polymerase elongation complex with unnatural base dPa-DsTP pair

SM: S96 S96

Structure of complex 8dh5

8dh5

T7 RNA polymerase elongation complex with unnatural base dPa-ATP mismatch

SM: ATP ATP ATP ATP

Structure of complex 8e85

8e85

Human DNA polymerase eta-DNA-rG-ended primer-dGMPNPP ternary mismatch complex with Mn2+

SM: XG4

Structure of complex 8e86

8e86

Human DNA polymerase eta-DNA-rC-ended primer-dGMPNPP ternary mismatch complex with Mn2+

SM: XG4

Structure of complex 8e87

8e87

Human DNA polymerase eta-DNA-rA-ended primer-dGMPNPP ternary mismatch complex with Mg2+

SM: XG4

Structure of complex 8e88

8e88

Human DNA polymerase eta-DNA-rU-ended primer-dGMPNPP ternary mismatch complex with Mg2+

SM: XG4

Structure of complex 8e8b

8e8b

Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:ground state at pH7.0 (K+ MES) with 1 Ca2+ ion

SM: DGT

Structure of complex 8e8c

8e8c

Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 30s

SM: DGT

Structure of complex 8e8d

8e8d

Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 60s

SM: DGT

Structure of complex 8e8j

8e8j

Human DNA polymerase eta-DNA-rG-ended primer-dGMPNPP ternary mismatch complex with Mg2+

SM: XG4

Structure of complex 8e8k

8e8k

Human DNA polymerase eta-DNA-rC-ended primer-dGMPNPP ternary mismatch complex with Mg2+

SM: XG4

Structure of complex 8ej3

8ej3

M. tuberculosis RNAP pause escaped complex with Bacillus subtilis NusG and GMPCPP

SM: G2P

Structure of complex 8eos

8eos

M. tuberculosis RNAP elongation complex with NusG and CMPCPP

SM: 2TM

Structure of complex 8exy

8exy

M. tuberculosis RNAP paused complex with B. subtilis NusG and GMPCPP

SM: G2P

Structure of complex 8g9l

8g9l

DNA initiation subcomplex of Xenopus laevis DNA polymerase alpha-primase

SM: DGT

Structure of complex 8gh6

8gh6

Bombyx mori R2 retrotransposon initiating target-primed reverse transcription

SM: TTP

Structure of complex 8gzh

8gzh

Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc

SM: CTP

Structure of complex 8sxt

8sxt

Structure of LINE-1 ORF2p with template:primer hybrid

SM: TTP

Structure of complex 8sy5

8sy5

E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dS-BTP base pair in the active site

SM: X0F

Structure of complex 8sy6

8sy6

E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-UTP base pair in the active site

SM: DGP UTP

Structure of complex 8sy7

8sy7

E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-STP base pair in the active site

SM: X0O

Structure of complex 8txo

8txo

E. coli DNA-directed RNA polymerase transcription elongation complex bound to the unnatural dZ-PTP base pair in the active site

SM: S9F

Structure of complex 8u8u

8u8u

Cryo-EM Structure of Cognate Substrate ATP Bound in the Entry Site (ES) of Human Mitochondrial Transcription Elongation Complex

SM: APC

Structure of complex 8u8v

8u8v

Cryo-EM structure of Substrate ATP Bound in the Insertion Site (IS) of Human Mitochondrial Transcription Elongation Complex

SM: APC

Structure of complex 8u9r

8u9r

STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION USING A FREE-ELECTRON LASER

SM: ATP

Structure of complex 8u9x

8u9x

STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION AT 3.0 A OF T834P MUTANT USING A FREE-ELECTRON LASER

SM: ATP

Structure of complex 8uks

8uks

RNA polymerase II elongation complex with Fapy-dG lesion soaking with CTP before chemistry

SM: CTP

Structure of complex 8urw

8urw

Cyanobacterial RNA polymerase elongation complex with NusG and CTP

SM: CTP

Structure of complex 8uw3

8uw3

Human LINE-1 retrotransposon ORF2 protein engaged with template RNA in elongation state

SM: TTP

Structure of complex 8v6g

8v6g

DNA initiation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase

SM: DGT

Structure of complex 8v6h

8v6h

DNA initiation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase

SM: DGT

Structure of complex 8w8p

8w8p

Thermus thermophilus initiation transcription complex containing CMPcPP in the post-translocated state

SM: 2TM