Complex 8u9r
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.34 |
| System mass | 522.81 kDa |
| Deposition year | 2023 |
| Molecule type | RNA/DNA/Protein |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 8u9r |
| Reference | Lin Guowu, Barnes Christopher O., Weiss Simon, Dutagaci Bercem, Qiu Chenxi, Feig Michael, Song Jihnu, Lyubimov Artem, Cohen Aina E., Kaplan Craig D., Calero Guillermo. 2024. Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser Proceedings of the National Academy of Sciences |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | ATP |
| Residue | . / 1806 |
| Chain | T / A |
| Non-redundant | True |
| Interacting RNA chains | M/R |
| RNA environment detailled | DNA, protein, ion |
| RNA environment global | RNA/DNA/Protein |
| RNA family chains | M/R: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 778.27 Å3 |
| Hydrophobicity | 0.026 |
| Hydrophilicity | 1.852 |
| Buriedness | 0.821 |
| Don/acc character | 0.703 |
| SiteScore | 1.082 |
| D Score | 0.829 |
| Kd | — |