Complex 7k9y
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.20 |
| System mass | 116.97 kDa |
| Deposition year | 2020 |
| Molecule type | RNA/DNA/Protein |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 7k9y |
| Reference | Lentzsch Alfred M., Stamos Jennifer L., Yao Jun, Russell Rick, Lambowitz Alan M.. 2021. Structural basis for template switching by a group II intron–encoded non-LTR-retroelement reverse transcriptase Journal of Biological Chemistry |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | DTP |
| Residue | . / 501 |
| Chain | I / A |
| Non-redundant | True |
| Interacting RNA chains | G/G |
| RNA environment detailled | DNA, protein, ion |
| RNA environment global | RNA/DNA/Protein |
| RNA family chains | G/G: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 582.07 Å3 |
| Hydrophobicity | 0.545 |
| Hydrophilicity | 1.452 |
| Buriedness | 0.860 |
| Don/acc character | 0.498 |
| SiteScore | 1.108 |
| D Score | 0.983 |
| Kd | — |
| Compound | DTP |
| Residue | . / 501 |
| Chain | M / D |
| Non-redundant | True |
| Interacting RNA chains | H/H |
| RNA environment detailled | DNA, protein, ion |
| RNA environment global | RNA/DNA/Protein |
| RNA family chains | H/H: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 618.09 Å3 |
| Hydrophobicity | 0.500 |
| Hydrophilicity | 1.439 |
| Buriedness | 0.847 |
| Don/acc character | 0.405 |
| SiteScore | 1.100 |
| D Score | 0.979 |
| Kd | — |