Harnessing RIBOnucleic acid - Small molecules Structures
Long Interspersed Nuclear Element 1 (LINE-1) reverse transcriptase ternary complex with hybrid duplex and dTTP
SM: TTP
T7 RNA polymerase elongation complex with unnatural base dDs-PaTP pair
SM: S8L
T7 RNA polymerase elongation complex with unnatural base dPa-DsTP pair
SM: S96
T7 RNA polymerase elongation complex with unnatural base dPa-ATP mismatch
SM: ATP
M. tuberculosis RNAP elongation complex with NusG and CMPCPP
SM: 2TM
M. tuberculosis RNAP paused complex with B. subtilis NusG and GMPCPP
SM: G2P
Structure of Beetroot dimer bound to DFAME
SM: X5R
Structure of Beetroot dimer bound to DFHO
SM: 747
Beetroot dimer bound to ThT
SM: TFX
Wobble Beetroot (A16U-U38G) dimer bound to DFHO
DNA initiation subcomplex of Xenopus laevis DNA polymerase alpha-primase
SM: DGT
Cryo-EM structure of Synechocystis sp. PCC 6803 CTP-bound RPitc
SM: CTP
Cryo-EM structure of the the NS5-NS3 RNA-elongation complex
SM: CDP
A new fluorescent RNA aptamer_III bound with N
SM: NI4
Monkeypox virus VP39 in complex with SAH and cap0
SM: SAH
Structural insights into human co-transcriptional capping - structure 6
SM: SAM
SARS-CoV-2 nsp10-16 methyltransferase in complex with Sangivamycin and m7GpppA-RNA (Cap0-RNA)
SM: SAM SGV
SARS-CoV-2 nsp10-16 methyltransferase in complex with Toyocamycin and m7GpppA-RNA (Cap0-RNA)
SM: TO1
RNA duplex bound with GpppA dinucleotide ligand
SM: G3A
GpppA dinucleotide ligand binding to RNA UC template
GpppA dinucleotide binding to RNA CU template
RNA duplex bound with GMP and AMP monomers
SM: 5GP AMP
RNA UU template binding to AMP monomer
SM: AMP
Structure of LINE-1 ORF2p with template:primer hybrid
RNA duplex bound with imidazolium bridged GA dinucleotide
SM: WZW
E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dS-BTP base pair in the active site
SM: X0F
E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-UTP base pair in the active site
SM: DGP UTP
E. coli DNA-directed RNA polymerase transcription elongation complex bound the unnatural dB-STP base pair in the active site
SM: X0O
Crystal structure of RNA device 43 truncation mutant 3 (U100C), holo state
SM: TAC
Cryo-EM structure of RNA device 43, holo state
E. coli DNA-directed RNA polymerase transcription elongation complex bound to the unnatural dZ-PTP base pair in the active site
SM: S9F
Cryo-EM Structure of Cognate Substrate ATP Bound in the Entry Site (ES) of Human Mitochondrial Transcription Elongation Complex
SM: APC
Cryo-EM structure of Substrate ATP Bound in the Insertion Site (IS) of Human Mitochondrial Transcription Elongation Complex
STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION USING A FREE-ELECTRON LASER
STRUCTURAL BASIS OF TRANSCRIPTION: RNA POLYMERASE II SUBSTRATE BINDING AND METAL COORDINATION AT 3.0 A OF T834P MUTANT USING A FREE-ELECTRON LASER
RNA polymerase II elongation complex with Fapy-dG lesion soaking with CTP before chemistry
Cyanobacterial RNA polymerase elongation complex with NusG and CTP
Human LINE-1 retrotransposon ORF2 protein engaged with template RNA in elongation state
DNA initiation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase
DNA initiation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase
Magnesium catalyzed primer extension product with 14mer primer and mixed phosphorothioate activated G monomer
SM: DGP
Cadmium catalyzed primer extension product with 14mer primer and mixed phosphorothioate activated G monomer
Thermus thermophilus initiation transcription complex containing CMPcPP in the post-translocated state
Structure of transcribing complex 2 (TC2), the initially transcribing complex with Pol II positioned 2nt downstream of TSS.
SM: W0F
Structure of transcribing complex 3 (TC3), the initially transcribing complex with Pol II positioned 3nt downstream of TSS.
Structure of transcribing complex 4 (TC4), the initially transcribing complex with Pol II positioned 4nt downstream of TSS.
Structure of transcribing complex 5 (TC5), the initially transcribing complex with Pol II positioned 5nt downstream of TSS.
Structure of transcribing complex 6 (TC6), the initially transcribing complex with Pol II positioned 6nt downstream of TSS.
Structure of transcribing complex 7 (TC7), the initially transcribing complex with Pol II positioned 7nt downstream of TSS.
Structure of transcribing complex 8 (TC8), the initially transcribing complex with Pol II positioned 8nt downstream of TSS.
Structure of transcribing complex 9 (TC9), the initially transcribing complex with Pol II positioned 9nt downstream of TSS.
De novo transcribing complex 10 (TC10), the early elongation complex with Pol II positioned 10nt downstream of TSS
De novo transcribing complex 11 (TC11), the early elongation complex with Pol II positioned 11nt downstream of TSS
De novo transcribing complex 12 (TC12), the early elongation complex with Pol II positioned 12nt downstream of TSS
De novo transcribing complex 13 (TC13), the early elongation complex with Pol II positioned 13nt downstream of TSS
De novo transcribing complex 14 (TC14), the early elongation complex with Pol II positioned 14nt downstream of TSS
De novo transcribing complex 15 (TC15), the early elongation complex with Pol II positioned 15nt downstream of TSS
De novo transcribing complex 16 (TC16), the early elongation complex with Pol II positioned 16nt downstream of TSS
De novo transcribing complex 17 (TC17), the early elongation complex with Pol II positioned 17nt downstream of TSS
CryoEM structure of compound HNC-1664 bound with RdRP-RNA complex of SARS-CoV-2
SM: A1LVZ
Current selection range: to
