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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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242 RNA-SM complexes found
Structure of complex 6hko

6hko

Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP

SM: G2P

Structure of complex 6hlq

6hlq

Yeast RNA polymerase I* elongation complex bound to nucleotide analog GMPCPP

SM: G2P

Structure of complex 6hlr

6hlr

Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP (core focused)

SM: G2P

Structure of complex 6n9u

6n9u

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) interacting with primase domains of two gp4 subunits bound to an RNA/DNA hybrid and dTTP (from LagS1)

SM: TTP

Structure of complex 6n9v

6n9v

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS1)

SM: TTP

Structure of complex 6i1l

6i1l

Crystal structure of FnCas12a in complex with a crRNA guide and ssDNA target

SM: CIT CIT CIT CIT CIT CIT

Structure of complex 6n9w

6n9w

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS2)

SM: TTP

Structure of complex 6n9x

6n9x

Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS3)

SM: TTP

Structure of complex 6oy5

6oy5

X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 3 min

SM: GTP

Structure of complex 6oy6

6oy6

X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter at 5 min

SM: GTP

Structure of complex 6p1s

6p1s

Post-catalytic nicked complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and newly incorporated AMP

SM: ATP

Structure of complex 6p1u

6p1u

Post-catalytic nicked complex of human DNA Polymerase Mu with 1-nt gapped substrate containing template 8OG and newly incorporated CMP

SM: CTP

Structure of complex 6p71

6p71

X-ray crystal structure of a bacterial reiterative transcription complex of pyrBI promoter

SM: UTP

Structure of complex 6rh3

6rh3

Cryo-EM structure of E. coli RNA polymerase elongation complex bound to CTP substrate

SM: CTP

Structure of complex 6upy

6upy

RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 2E

SM: APC

Structure of complex 6usr

6usr

Telomerase Reverse Transcriptase ternary complex, TERT:DNA:dGpCpp

SM: G2P

Structure of complex 6uu0

6uu0

E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching GTP ("Fresh" crystal soaked with GTP for 1 hour)

SM: GTP

Structure of complex 6uu1

6uu1

E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Fresh" crystal soaked with CTP, GTP, and ddTTP for 30 minutes)

SM: CTP

Structure of complex 6uu2

6uu2

E. coli sigma-S transcription initiation complex with 3-nt RNA ("Old" crystal soaked with GTP and ATP for 30 minutes)

SM: GTP

Structure of complex 6uu3

6uu3

E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Old" crystal soaked with GTP, ATP, CTP, and ddTTP for 30 minutes)

SM: D4M

Structure of complex 6uu4

6uu4

E. coli sigma-S transcription initiation complex with a 3-nt RNA ("old" crystal soaked with GTP and dinucleotide GpA for 30 minutes)

SM: GTP

Structure of complex 6uu6

6uu6

E. coli sigma-S transcription initiation complex with a 4-nt RNA and a UTP ("Old" crystal soaked with UTP, ddCTP, and dinucleotide ApG for 30 minutes)

SM: UTP

Structure of complex 6uu9

6uu9

E. coli mutant sigma-S transcription initiation complex with an 8-nt RNA ("Fresh" mutant crystal soaked with GTP, UTP, CTP, and ddATP for 30 minutes)

SM: 2DA

Structure of complex 6uuc

6uuc

E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching ATP ("Fresh" crystal soaked with ATP for 2 hours)

SM: ATP

Structure of complex 6wox

6wox

Thermus thermophilus RNA polymerase initially transcribing complex with 2'dCTP

SM: DCP

Structure of complex 6woy

6woy

Thermus thermophilus RNA polymerase initially transcribing complex with 3'dCTP

SM: CH1

Structure of complex 6ymw

6ymw

Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex

SM: P5E

Structure of complex 7m8c

7m8c

Human DNA Pol eta S113A with rA-ended primer and dATP: in crystallo reaction for 230 s

SM: DTP

Structure of complex 7d2l

7d2l

Crystal structure of the Cas12i1 R-loop complex before target DNA cleavage

SM: CIT

Structure of complex 7d3j

7d3j

Crystal structure of the Cas12i1 R-loop complex after target DNA cleavage

SM: CIT

Structure of complex 7eu9

7eu9

Crystal structure of the selenomethionine(SeMet)-derived Cas12i1 R-loop complex before target DNA cleavage

SM: CIT

Structure of complex 7eh0

7eh0

Thermus thermophilus RNA polymerase transcription initiation complex containing a template-strand purine at position TSS-2, UpA RNA primer and CMPcPP

SM: 2TM

Structure of complex 7eh1

7eh1

Thermus thermophilus transcription initiation complex containing a template-strand purine at position TSS-2, GpG RNA primer, and CMPcPP

SM: 2TM

Structure of complex 7k9y

7k9y

GsI-IIC RT Template-Switching Complex (twinned)

SM: DTP DTP

Structure of complex 7kqn

7kqn

Ternary complex of TERT (telomerase reverse transcriptase) with RNA template, DNA primer, an incoming dGTP and a downstream hybrid duplex

SM: DGT DGT

Structure of complex 7m8b

7m8b

Human DNA Pol eta S113A with rA-ended primer and dATP: in crystallo reaction for 140 s

SM: DTP

Structure of complex 7m7m

7m7m

Human DNA Pol eta with rA-ended primer and dAMPNPP

SM: DZ4

Structure of complex 7m7r

7m7r

Human DNA Pol eta S113A with rA-ended primer and dAMPNPP

SM: DZ4

Structure of complex 7m89

7m89

Human DNA Pol eta S113A with rA-ended primer and dATP: in crystallo reaction for 0 s

SM: DTP

Structure of complex 7m8a

7m8a

Human DNA Pol eta S113A with rA-ended primer and dATP: in crystallo reaction for 40 s

SM: DTP

Structure of complex 7m8d

7m8d

Human DNA Pol eta S113A with rA-ended primer and dATP: in crystallo reaction for 300 s

SM: DTP

Structure of complex 7mkn

7mkn

Escherichia coli RNA polymerase and RapA elongation complex

SM: 2TM

Structure of complex 7mko

7mko

Escherichia coli RNA polymerase elongation complex

SM: 2TM

Structure of complex 7n2m

7n2m

Crystal structure of DNA polymerase alpha catalytic core in complex with dCTP and template/primer having T-C mismatch at the post-insertion site

SM: DCP

Structure of complex 7y7r

7y7r

QDE-1 in complex with DNA template, RNA primer and 3'-dGTP

SM: GTP GTP

Structure of complex 7y7s

7y7s

QDE-1 in complex with DNA template, RNA primer and AMPNPP

SM: ZAN ZAN

Structure of complex 7y7t

7y7t

QDE-1 in complex with 12nt DNA template, ATP and 3'-dGTP

SM: GTP

Structure of complex 7vba

7vba

Structure of the pre state human RNA Polymerase I Elongation Complex

SM: 2TM

Structure of complex 8e86

8e86

Human DNA polymerase eta-DNA-rC-ended primer-dGMPNPP ternary mismatch complex with Mn2+

SM: XG4

Structure of complex 8e87

8e87

Human DNA polymerase eta-DNA-rA-ended primer-dGMPNPP ternary mismatch complex with Mg2+

SM: XG4

Structure of complex 8e88

8e88

Human DNA polymerase eta-DNA-rU-ended primer-dGMPNPP ternary mismatch complex with Mg2+

SM: XG4

Structure of complex 8c8j

8c8j

Long Interspersed Nuclear Element 1 (LINE-1) reverse transcriptase ternary complex with hybrid duplex and dTTP

SM: TTP

Structure of complex 8e8b

8e8b

Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:ground state at pH7.0 (K+ MES) with 1 Ca2+ ion

SM: DGT

Structure of complex 8e8c

8e8c

Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 30s

SM: DGT

Structure of complex 8e8d

8e8d

Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 60s

SM: DGT

Structure of complex 8e8e

8e8e

Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 90s

SM: DGT

Structure of complex 8e8f

8e8f

Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 120s

SM: DGT

Structure of complex 8e8g

8e8g

Human DNA polymerase eta-DNA-rU-ended primer ternary mismatch complex:reaction with 10 mM Mn2+ for 180s

SM: DGT

Structure of complex 8dh1

8dh1

T7 RNA polymerase elongation complex with unnatural base dDs-PaTP pair

SM: S8L

Structure of complex 8dh4

8dh4

T7 RNA polymerase elongation complex with unnatural base dPa-DsTP pair

SM: S96 S96