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Harnessing RIBOnucleic acid - Small molecules Structures

RNA-SM complexes

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218 RNA-SM complexes found
Structure of complex 6cab

6cab

RNA-dGMP complex with Sr ion

SM: 5GP 5GP 5GP 5GP

Structure of complex 6dta

6dta

Bacteriophage N4 RNA polymerase II elongation complex 2

SM: GTP

Structure of complex 6i1l

6i1l

Crystal structure of FnCas12a in complex with a crRNA guide and ssDNA target

SM: CIT CIT CIT CIT CIT CIT

Structure of complex 6kwr

6kwr

Crystal structure of enterovirus 71 polymerase elongation complex (ddCTP form)

SM: DCT

Structure of complex 6qcv

6qcv

Crystal structure of influenza B polymerase initiation state with capped 14-mer RNA primer and CTP

SM: CTP

Structure of complex 6u6j

6u6j

RNA-monomer complex containing pyrophosphate linkage

SM: EQ4 EQ4

Structure of complex 6u7y

6u7y

RNA hairpin structure containing one TNA nucleotide as template

SM: C5P

Structure of complex 6u7z

6u7z

RNA hairpin structure containing one TNA nucleotide as primer

SM: C5P

Structure of complex 6u89

6u89

RNA duplex, bound with TNA monomer

SM: TG TG

Structure of complex 6u8f

6u8f

RNA hairpin, bound with TNA monomer

SM: TG

Structure of complex 6u8u

6u8u

RNA duplex bound with TNA 3'-3' imidazolium dimer

SM: Q1V Q1V

Structure of complex 6uej

6uej

Crystal structure of human zinc finger antiviral protein bound to RNA

SM: SPM

Structure of complex 6upy

6upy

RNA polymerase II elongation complex with 5-guanidinohydantoin lesion in state 2E

SM: APC

Structure of complex 6uu0

6uu0

E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching GTP ("Fresh" crystal soaked with GTP for 1 hour)

SM: GTP

Structure of complex 6uu1

6uu1

E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Fresh" crystal soaked with CTP, GTP, and ddTTP for 30 minutes)

SM: CTP

Structure of complex 6uu2

6uu2

E. coli sigma-S transcription initiation complex with 3-nt RNA ("Old" crystal soaked with GTP and ATP for 30 minutes)

SM: GTP

Structure of complex 6uu3

6uu3

E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Old" crystal soaked with GTP, ATP, CTP, and ddTTP for 30 minutes)

SM: D4M

Structure of complex 6uu4

6uu4

E. coli sigma-S transcription initiation complex with a 3-nt RNA ("old" crystal soaked with GTP and dinucleotide GpA for 30 minutes)

SM: GTP

Structure of complex 6uu6

6uu6

E. coli sigma-S transcription initiation complex with a 4-nt RNA and a UTP ("Old" crystal soaked with UTP, ddCTP, and dinucleotide ApG for 30 minutes)

SM: UTP

Structure of complex 6uu9

6uu9

E. coli mutant sigma-S transcription initiation complex with an 8-nt RNA ("Fresh" mutant crystal soaked with GTP, UTP, CTP, and ddATP for 30 minutes)

SM: 2DA

Structure of complex 6uuc

6uuc

E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching ATP ("Fresh" crystal soaked with ATP for 2 hours)

SM: ATP

Structure of complex 6xki

6xki

Crystal structure of eIF4A-I in complex with RNA bound to des-MePateA, a pateamine A analog

SM: V6D

Structure of complex 6ymw

6ymw

Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex

SM: P5E

Structure of complex 7a3y

7a3y

RNA duplex with a cytosine bulge in complex with berberine

SM: BER

Structure of complex 7abf

7abf

Human pre-Bact-1 spliceosome core structure

SM: IHP

Structure of complex 7ed5

7ed5

A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase

SM: AT9

Structure of complex 7edt

7edt

RNA duplex containing CC mispairs

SM: SPM

Structure of complex 7eh0

7eh0

Thermus thermophilus RNA polymerase transcription initiation complex containing a template-strand purine at position TSS-2, UpA RNA primer and CMPcPP

SM: 2TM

Structure of complex 7eh1

7eh1

Thermus thermophilus transcription initiation complex containing a template-strand purine at position TSS-2, GpG RNA primer, and CMPcPP

SM: 2TM

Structure of complex 7k9y

7k9y

GsI-IIC RT Template-Switching Complex (twinned)

SM: DTP DTP

Structure of complex 7kuk

7kuk

High resolution RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G

SM: GP3 GP3

Structure of complex 7kum

7kum

LNA modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G

SM: GP3 GP3

Structure of complex 7kun

7kun

2'-F modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G

SM: GP3 GP3

Structure of complex 7kuo

7kuo

FANA modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G

SM: GP3 GP3

Structure of complex 7kup

7kup

2'-OMe modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G

SM: GP3 GP3

Structure of complex 7l6r

7l6r

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1), S-Adenosyl-L-homocysteine (SAH) and Manganese (Mn).

SM: SAH

Structure of complex 7l6t

7l6t

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1), S-Adenosyl-L-homocysteine (SAH) and two Magnesium (Mg) ions.

SM: SAH

Structure of complex 7lne

7lne

ANA modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G

SM: GP3 GP3

Structure of complex 7lnf

7lnf

3'-deoxy modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G

SM: GP3 GP3

Structure of complex 7lng

7lng

TNA modification at 3' end of RNA primer complex with guanosine dinucleotide ligand G(5')ppp(5')G

SM: GP3 GP3

Structure of complex 7mkt

7mkt

Crystal structure of r(GU)11G-NMM complex

SM: MMP

Structure of complex 7om7

7om7

Thosea asigna virus RdRP domain in complex with RNA and nucleotide UMPNPP

SM: 2KH 2KH

Structure of complex 7tuv

7tuv

Crystal structure of the exoribonucleolytic module of T. brucei RRP44

SM: U5P

Structure of complex 7u87

7u87

Product of 13mer primer with activated G monomer diastereomer 1

SM: LXI LXI

Structure of complex 7u88

7u88

Product of 13mer primer with activated G monomer diastereomer 2

SM: LXI LXI

Structure of complex 7u89

7u89

Product of 14mer primer with activated G monomer diastereomer 1

SM: LXI LXI

Structure of complex 7u8a

7u8a

Product of 14mer primer with activated G monomer diastereomer 2

SM: LXI LXI

Structure of complex 7u8b

7u8b

Product of 14mer primer with activated asymmetric GA dimer diastereomer 1

SM: LXR

Structure of complex 7uo4

7uo4

SARS-CoV-2 replication-transcription complex bound to Remdesivir triphosphate, in a pre-catalytic state

SM: NWX

Structure of complex 7uo7

7uo7

SARS-CoV-2 replication-transcription complex bound to ATP, in a pre-catalytic state

SM: ATP

Structure of complex 7uo9

7uo9

SARS-CoV-2 replication-transcription complex bound to UTP, in a pre-catalytic state

SM: UTP

Structure of complex 7uob

7uob

SARS-CoV-2 replication-transcription complex bound to GTP, in a pre-catalytic state

SM: GTP

Structure of complex 7uoe

7uoe

SARS-CoV-2 replication-transcription complex bound to CTP, in a pre-catalytic state

SM: CTP

Structure of complex 7w9s

7w9s

Crystal structure of the enterovirus 71 polymerase elongation complex (C1S3 form)

SM: CTP

Structure of complex 7xd9

7xd9

Crystal Structure of Dengue Virus serotype 2 (DENV2) Polymerase Elongation Complex (CTP Form)

SM: CTP CTP CTP CTP CTP CTP

Structure of complex 7y7p

7y7p

QDE-1 in complex with RNA template, RNA primer and AMPNPP

SM: ZAN ZAN

Structure of complex 7y7q

7y7q

QDE-1 in complex with RNA template, RNA primer and 3'-dGTP

SM: GTP GTP GTP

Structure of complex 7y7r

7y7r

QDE-1 in complex with DNA template, RNA primer and 3'-dGTP

SM: GTP GTP

Structure of complex 7y7s

7y7s

QDE-1 in complex with DNA template, RNA primer and AMPNPP

SM: ZAN ZAN

Structure of complex 7y7t

7y7t

QDE-1 in complex with 12nt DNA template, ATP and 3'-dGTP

SM: GTP