Complex 7tuv
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.23 |
| System mass | 85.99 kDa |
| Deposition year | 2022 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 7tuv |
| Reference | Cesaro Giovanna, da Soler Heloisa Tramontin, Guerra-Slompo Eloise Pavão, Haouz Ahmed, Legrand Pierre, Zanchin Nilson Ivo Tonin, Guimaraes Beatriz Gomes. 2023. Trypanosoma brucei RRP44: a versatile enzyme for processing structured and non-structured RNA substrates Nucleic Acids Research |
| Equivalence Class |
NR_all_12473.1
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | U5P |
| Residue | . / 1001 |
| Chain | C / A |
| Non-redundant | True |
| Interacting RNA chains | B/B |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | B/B: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 207.17 Å3 |
| Hydrophobicity | 1.942 |
| Hydrophilicity | 0.712 |
| Buriedness | 0.815 |
| Don/acc character | 0.768 |
| SiteScore | 0.782 |
| D Score | 0.736 |
| Kd | — |