Complex 7y7p
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.70 |
| System mass | 249.14 kDa |
| Deposition year | 2022 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 7y7p |
| Reference | Cui Ruixue, Li Hao, Zhao Jin, Li Xuhang, Gan Jianhua, Ma Jinbiao. 2022. Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1 Nucleic Acids Research |
| Equivalence Class |
NR_all_67617.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | ZAN |
| Residue | . / 1504 |
| Chain | J / A |
| Non-redundant | False |
| Interacting RNA chains | D/D, C/C |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | C/C: synthetic construct, D/D: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 78.89 Å3 |
| Hydrophobicity | 0.181 |
| Hydrophilicity | 1.354 |
| Buriedness | 0.978 |
| Don/acc character | 0.443 |
| SiteScore | 0.940 |
| D Score | 0.769 |
| Kd | — |
| Compound | ZAN |
| Residue | . / 1506 |
| Chain | P / B |
| Non-redundant | False |
| Interacting RNA chains | F/J, E/E |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | E/E: synthetic construct, F/J: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 285.03 Å3 |
| Hydrophobicity | 0.863 |
| Hydrophilicity | 0.946 |
| Buriedness | 0.785 |
| Don/acc character | 1.066 |
| SiteScore | 0.974 |
| D Score | 0.972 |
| Kd | — |