Complex 7y7q
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.05 |
| System mass | 247.63 kDa |
| Deposition year | 2022 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 7y7q |
| Reference | Cui Ruixue, Li Hao, Zhao Jin, Li Xuhang, Gan Jianhua, Ma Jinbiao. 2022. Structural insights into the dual activities of the two-barrel RNA polymerase QDE-1 Nucleic Acids Research |
| Equivalence Class |
NR_all_35958.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | GTP |
| Residue | . / 2005 |
| Chain | J / A |
| Non-redundant | True |
| Interacting RNA chains | C/C, D/D |
| RNA environment detailled | protein, ion |
| RNA environment global | RNA/Protein |
| RNA family chains | C/C: synthetic construct, D/D: synthetic construct |
| RNA family global | synthetic construct |
| Volume | - |
| Hydrophobicity | - |
| Hydrophilicity | - |
| Buriedness | - |
| Don/acc character | - |
| SiteScore | - |
| D Score | - |
| Kd | — |
| Compound | GTP |
| Residue | . / 1502 |
| Chain | L / B |
| Non-redundant | True |
| Interacting RNA chains | E/E |
| RNA environment detailled | protein, ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | E/E: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 646.90 Å3 |
| Hydrophobicity | 0.111 |
| Hydrophilicity | 1.626 |
| Buriedness | 0.773 |
| Don/acc character | 0.678 |
| SiteScore | 1.050 |
| D Score | 0.874 |
| Kd | — |
| Compound | GTP |
| Residue | . / 1509 |
| Chain | S / B |
| Non-redundant | False |
| Interacting RNA chains | E/E |
| RNA environment detailled | protein, ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | E/E: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 793.36 Å3 |
| Hydrophobicity | 0.397 |
| Hydrophilicity | 1.825 |
| Buriedness | 0.787 |
| Don/acc character | 0.799 |
| SiteScore | 1.059 |
| D Score | 0.817 |
| Kd | — |