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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9v7o

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 3.06
System mass 276.01 kDa
Deposition year 2025
Molecule type RNA
# RNA entities 1
Organism Azoarcus
RCSB PDB Entry 9v7o
Reference Hong Yibao, Liu Jiashu, Zhang Xiaojing, Liu Ji, Li Shanshan, Zhang Kaiming. 2026. Pre-splicing conformation and stepwise circularization of a group I intron in Azoarcus pre-tRNA Nature Communications
Equivalence Class NR_all_44873.1
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound GMP
Residue . / 301
Chain D / B
Non-redundant True
Interacting RNA chains A/B
RNA environment detailled ion
RNA environment global RNA
RNA family chains A/B: tRNA
RNA family global tRNA
Volume 676.40 Å3
Hydrophobicity 0.142
Hydrophilicity 1.384
Buriedness 0.775
Don/acc character 2.716
SiteScore 1.202
D Score 0.954
Kd