Complex 9gzn
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.50 |
| System mass | 213.39 kDa |
| Deposition year | 2024 |
| Molecule type | RNA/DNA/Protein |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 9gzn |
| Reference | Shen Jiayu, Goovaerts Quinten, Ajjugal Yogeeshwar, De Wijngaert Brent, Das Kalyan, Patel Smita S.. 2025. Human mitochondrial RNA polymerase structures reveal transcription start site and slippage mechanism Molecular Cell |
| Equivalence Class |
NR_all_04288.8
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | GTP |
| Residue | . / 1301 |
| Chain | F / A |
| Non-redundant | True |
| Interacting RNA chains | E/R |
| RNA environment detailled | DNA, protein, ion |
| RNA environment global | RNA/DNA/Protein |
| RNA family chains | E/R: RNA/DNA_hybrid |
| RNA family global | RNA/DNA_hybrid |
| Volume | 799.88 Å3 |
| Hydrophobicity | 0.697 |
| Hydrophilicity | 1.324 |
| Buriedness | 0.836 |
| Don/acc character | 0.757 |
| SiteScore | 1.092 |
| D Score | 1.010 |
| Kd | — |