HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Complex 8k2d

System information

Experimental technique Electron Microscopy
Experimental resolution 3.20
System mass 3327.24 kDa
Deposition year 2023
Molecule type RNA/Protein
# RNA entities 1
Organism Saccharomyces
RCSB PDB Entry 8k2d
Reference Li Xiang, Wang Mengjiao, Denk Timo, Buschauer Robert, Li Yi, Beckmann Roland, Cheng Jingdong. . Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline Nature Communications

Compound GDP
Residue . / 902
Chain ZC / CD
Non-redundant True
Interacting RNA chains B/C1
Volume 451.73 Å3
Hydrophobicity 0.195
Hydrophilicity 1.757
Buriedness 0.744
Don/acc character 0.920
SiteScore 1.031
D Score 0.814

Compound T1C
Residue . / 3401
Chain HC / C1
Non-redundant True
Interacting RNA chains B/C1, A/C2
Volume 388.96 Å3
Hydrophobicity 0.251
Hydrophilicity 1.078
Buriedness 0.653
Don/acc character 2.776
SiteScore 1.120
D Score 0.980

Compound T1C
Residue . / 3402
Chain IC / C1
Non-redundant True
Interacting RNA chains B/C1
Volume 459.62 Å3
Hydrophobicity 0.180
Hydrophilicity 1.256
Buriedness 0.718
Don/acc character 2.703
SiteScore 1.163
D Score 0.961

Compound T1C
Residue . / 3403
Chain JC / C1
Non-redundant True
Interacting RNA chains B/C1
Volume 779.30 Å3
Hydrophobicity 0.278
Hydrophilicity 1.152
Buriedness 0.721
Don/acc character 1.798
SiteScore 1.166
D Score 0.997

Compound T1C
Residue . / 3404
Chain KC / C1
Non-redundant True
Interacting RNA chains B/C1, D/C3
Volume 724.42 Å3
Hydrophobicity 0.327
Hydrophilicity 1.067
Buriedness 0.664
Don/acc character 1.123
SiteScore 0.977
D Score 0.991

Compound T1C
Residue . / 3405
Chain LC / C1
Non-redundant True
Interacting RNA chains B/C1
Volume 692.52 Å3
Hydrophobicity 0.195
Hydrophilicity 1.118
Buriedness 0.659
Don/acc character 0.979
SiteScore 0.974
D Score 0.971

Compound T1C
Residue . / 3406
Chain MC / C1
Non-redundant True
Interacting RNA chains B/C1
Volume 351.23 Å3
Hydrophobicity 0.058
Hydrophilicity 1.679
Buriedness 0.656
Don/acc character 0.943
SiteScore 0.823
D Score 0.786