Complex 7rex
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.60 |
| System mass | 33.72 kDa |
| Deposition year | 2021 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | Carnobacterium |
| RCSB PDB Entry | 7rex |
| Reference | Schroeder Griffin M., Cavender Chapin E., Blau Maya E., Jenkins Jermaine L., Mathews David H., Wedekind Joseph E.. 2022. A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control Nature Communications |
| Equivalence Class |
NR_all_07310.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | PRF |
| Residue | . / 101 |
| Chain | D / A |
| Non-redundant | True |
| Interacting RNA chains | A/A |
| RNA environment detailled | other |
| RNA environment global | RNA/Other |
| RNA family chains | A/A: riboswitch |
| RNA family global | riboswitch |
| Volume | 395.82 Å3 |
| Hydrophobicity | 0.501 |
| Hydrophilicity | 1.114 |
| Buriedness | 0.678 |
| Don/acc character | 0.996 |
| SiteScore | 1.137 |
| D Score | 0.984 |
| Kd | — |
| Compound | PRF |
| Residue | . / 102 |
| Chain | E / A |
| Non-redundant | False |
| Interacting RNA chains | A/A |
| RNA environment detailled | other |
| RNA environment global | RNA/Other |
| RNA family chains | A/A: riboswitch |
| RNA family global | riboswitch |
| Volume | 360.84 Å3 |
| Hydrophobicity | 0.537 |
| Hydrophilicity | 1.336 |
| Buriedness | 0.743 |
| Don/acc character | 0.685 |
| SiteScore | 1.180 |
| D Score | 0.950 |
| Kd | — |
| Compound | PRF |
| Residue | . / 101 |
| Chain | I / B |
| Non-redundant | False |
| Interacting RNA chains | B/B |
| RNA environment detailled | other |
| RNA environment global | RNA/Other |
| RNA family chains | B/B: riboswitch |
| RNA family global | riboswitch |
| Volume | 422.23 Å3 |
| Hydrophobicity | 0.591 |
| Hydrophilicity | 1.156 |
| Buriedness | 0.701 |
| Don/acc character | 0.715 |
| SiteScore | 1.152 |
| D Score | 0.983 |
| Kd | — |
| Compound | PRF |
| Residue | . / 102 |
| Chain | J / B |
| Non-redundant | False |
| Interacting RNA chains | B/B |
| RNA environment detailled | other |
| RNA environment global | RNA/Other |
| RNA family chains | B/B: riboswitch |
| RNA family global | riboswitch |
| Volume | 334.43 Å3 |
| Hydrophobicity | 0.629 |
| Hydrophilicity | 1.386 |
| Buriedness | 0.757 |
| Don/acc character | 0.562 |
| SiteScore | 1.178 |
| D Score | 0.928 |
| Kd | — |
| Compound | PRF |
| Residue | . / 101 |
| Chain | K / C |
| Non-redundant | True |
| Interacting RNA chains | C/C |
| RNA environment detailled | other |
| RNA environment global | RNA/Other |
| RNA family chains | C/C: riboswitch |
| RNA family global | riboswitch |
| Volume | 408.17 Å3 |
| Hydrophobicity | 0.506 |
| Hydrophilicity | 1.122 |
| Buriedness | 0.715 |
| Don/acc character | 0.946 |
| SiteScore | 1.162 |
| D Score | 1.003 |
| Kd | — |
| Compound | PRF |
| Residue | . / 102 |
| Chain | L / C |
| Non-redundant | False |
| Interacting RNA chains | C/C |
| RNA environment detailled | other |
| RNA environment global | RNA/Other |
| RNA family chains | C/C: riboswitch |
| RNA family global | riboswitch |
| Volume | 315.22 Å3 |
| Hydrophobicity | 0.527 |
| Hydrophilicity | 1.156 |
| Buriedness | 0.710 |
| Don/acc character | 0.658 |
| SiteScore | 1.105 |
| D Score | 0.921 |
| Kd | — |