Complex 7of6

Legend

Pocket colors by molecule type

RNA

Protein

DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique	Electron Microscopy
Experimental resolution	2.60
System mass	1801.02 kDa
Deposition year	2021
Molecule type	RNA/Protein
# RNA entities	1
Organism	Homo
RCSB PDB Entry	7of6
Reference	Hillen Hauke S., Lavdovskaia Elena, Nadler Franziska, Hanitsch Elisa, Linden Andreas, Bohnsack Katherine E., Urlaub Henning, Richter-Dennerlein Ricarda. 2021. Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling Nature Communications
Equivalence Class	NR_all_12763.37 BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

Favourable

Intermediate

Unfavourable

Not available

Score	Threshold	Meaning
SiteScore	< 0.8	Non-drug binding site
SiteScore	0.8 – 1.0	Potential drug binding site
SiteScore	> 1.0	Promising binding site
D Score	< 0.83	Undruggable
D Score	0.83 – 0.98	Difficult
D Score	> 0.98	Druggable

Tick a pocket below to highlight it in the 3D structure above.

Pocket 1

Compound	GTP
Residue	. / 3386
Chain	KE / A
Non-redundant	True
Interacting RNA chains	K/A
RNA environment detailled	protein
RNA environment global	RNA/Protein
RNA family chains	K/A: rRNA
RNA family global	rRNA
Volume	222.61 Å³
Hydrophobicity	0.268
Hydrophilicity	1.253
Buriedness	0.702
Don/acc character	1.462
SiteScore	0.804
D Score	0.794
Kd	—

Pocket 2

Compound	GTP
Residue	. / 3387
Chain	LE / A
Non-redundant	True
Interacting RNA chains	K/A
RNA environment detailled	protein
RNA environment global	RNA/Protein
RNA family chains	K/A: rRNA
RNA family global	rRNA
Volume	299.78 Å³
Hydrophobicity	0.140
Hydrophilicity	1.164
Buriedness	0.654
Don/acc character	1.864
SiteScore	1.047
D Score	0.859
Kd	—