Complex 7of2
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.70 |
| System mass | 1853.05 kDa |
| Deposition year | 2021 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Homo |
| RCSB PDB Entry | 7of2 |
| Reference | Hillen Hauke S., Lavdovskaia Elena, Nadler Franziska, Hanitsch Elisa, Linden Andreas, Bohnsack Katherine E., Urlaub Henning, Richter-Dennerlein Ricarda. 2021. Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling Nature Communications |
| Equivalence Class |
NR_all_12763.37
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | GTP |
| Residue | . / 3382 |
| Chain | JE / A |
| Non-redundant | True |
| Interacting RNA chains | K/A |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | K/A: rRNA |
| RNA family global | rRNA |
| Volume | 225.35 Å3 |
| Hydrophobicity | 0.306 |
| Hydrophilicity | 1.222 |
| Buriedness | 0.696 |
| Don/acc character | 1.594 |
| SiteScore | 0.804 |
| D Score | 0.765 |
| Kd | — |
| Compound | GTP |
| Residue | . / 3383 |
| Chain | KE / A |
| Non-redundant | True |
| Interacting RNA chains | K/A |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | K/A: rRNA |
| RNA family global | rRNA |
| Volume | 338.88 Å3 |
| Hydrophobicity | 0.107 |
| Hydrophilicity | 1.163 |
| Buriedness | 0.649 |
| Don/acc character | 1.759 |
| SiteScore | 1.117 |
| D Score | 0.950 |
| Kd | — |