Complex 4v8c
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.30 |
| System mass | 4520.99 kDa |
| Deposition year | 2011 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 4v8c |
| Reference | Demeshkina Natalia, Jenner Lasse, Westhof Eric, Yusupov Marat, Yusupova Gulnara. 2012. A new understanding of the decoding principle on the ribosome Nature |
| Equivalence Class |
NR_all_65795.87
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | PAR |
| Residue | . / 1841 |
| Chain | IHB / CA |
| Non-redundant | True |
| Interacting RNA chains | IB/CA |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | IB/CA: rRNA |
| RNA family global | rRNA |
| Volume | 280.92 Å3 |
| Hydrophobicity | 0.083 |
| Hydrophilicity | 1.391 |
| Buriedness | 0.696 |
| Don/acc character | 1.780 |
| SiteScore | 1.075 |
| D Score | 0.810 |
| Kd | — |
| Compound | PAR |
| Residue | . / 1805 |
| Chain | CQB / DA |
| Non-redundant | True |
| Interacting RNA chains | HC/DA |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | HC/DA: rRNA |
| RNA family global | rRNA |
| Volume | 343.34 Å3 |
| Hydrophobicity | 0.083 |
| Hydrophilicity | 0.991 |
| Buriedness | 0.660 |
| Don/acc character | 2.342 |
| SiteScore | 1.112 |
| D Score | 0.984 |
| Kd | — |