Complex 4lel
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.90 |
| System mass | 4435.75 kDa |
| Deposition year | 2013 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | Thermus |
| RCSB PDB Entry | 4lel |
| Reference | Maehigashi Tatsuya, Dunkle Jack A., Miles Stacey J., Dunham Christine M.. 2014. Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops Proceedings of the National Academy of Sciences |
| Equivalence Class |
NR_all_65795.87
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | PAR |
| Residue | . / 1666 |
| Chain | VF / QA |
| Non-redundant | True |
| Interacting RNA chains | A/QA |
| RNA environment detailled | protein |
| RNA environment global | RNA/Protein |
| RNA family chains | A/QA: rRNA |
| RNA family global | rRNA |
| Volume | 299.10 Å3 |
| Hydrophobicity | 0.074 |
| Hydrophilicity | 1.107 |
| Buriedness | 0.699 |
| Don/acc character | 2.312 |
| SiteScore | 1.082 |
| D Score | 0.910 |
| Kd | — |
| Compound | PAR |
| Residue | . / 1671 |
| Chain | MS / XA |
| Non-redundant | True |
| Interacting RNA chains | DB/XA |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | DB/XA: rRNA |
| RNA family global | rRNA |
| Volume | 343.34 Å3 |
| Hydrophobicity | 0.122 |
| Hydrophilicity | 1.116 |
| Buriedness | 0.721 |
| Don/acc character | 2.371 |
| SiteScore | 1.046 |
| D Score | 0.855 |
| Kd | — |