Complex 3fu2
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 2.85 |
| System mass | 33.40 kDa |
| Deposition year | 2009 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 3fu2 |
| Reference | Klein Daniel J, Edwards Thomas E, Ferré-D'Amaré Adrian R. 2009. Cocrystal structure of a class I preQ1 riboswitch reveals a pseudoknot recognizing an essential hypermodified nucleobase Nature Structural & Molecular Biology |
| Equivalence Class |
NR_all_95363.6
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | PRF |
| Residue | . / 101 |
| Chain | D / A |
| Non-redundant | False |
| Interacting RNA chains | A/A |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | A/A: riboswitch |
| RNA family global | riboswitch |
| Volume | 273.71 Å3 |
| Hydrophobicity | 0.266 |
| Hydrophilicity | 1.206 |
| Buriedness | 0.721 |
| Don/acc character | 1.680 |
| SiteScore | 1.165 |
| D Score | 0.980 |
| Kd | 20nM |
| Compound | PRF |
| Residue | . / 101 |
| Chain | J / B |
| Non-redundant | False |
| Interacting RNA chains | B/B |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | B/B: riboswitch |
| RNA family global | riboswitch |
| Volume | 256.22 Å3 |
| Hydrophobicity | 0.247 |
| Hydrophilicity | 1.136 |
| Buriedness | 0.699 |
| Don/acc character | 1.915 |
| SiteScore | 1.151 |
| D Score | 0.989 |
| Kd | 20nM |
| Compound | PRF |
| Residue | . / 101 |
| Chain | M / C |
| Non-redundant | False |
| Interacting RNA chains | C/C |
| RNA environment detailled | RNA-only |
| RNA environment global | RNA |
| RNA family chains | C/C: riboswitch |
| RNA family global | riboswitch |
| Volume | 267.20 Å3 |
| Hydrophobicity | 0.370 |
| Hydrophilicity | 1.152 |
| Buriedness | 0.712 |
| Don/acc character | 2.050 |
| SiteScore | 1.159 |
| D Score | 0.991 |
| Kd | 20nM |