Complex 1uvn
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | X-ray |
| Experimental resolution | 3.00 |
| System mass | 233.62 kDa |
| Deposition year | 2004 |
| Molecule type | RNA/Protein |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 1uvn |
| Reference | Salgado Paula S., Makeyev Eugene V., Butcher Sarah J., Bamford Dennis H., Stuart David I., Grimes Jonathan M.. 2004. The Structural Basis for RNA Specificity and Ca2+ Inhibition of an RNA-Dependent RNA Polymerase Structure |
| Equivalence Class |
NR_all_31949.3
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | GTP |
| Residue | . / 1665 |
| Chain | G / A |
| Non-redundant | True |
| Interacting RNA chains | B/B |
| RNA environment detailled | protein, ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | B/B: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 257.59 Å3 |
| Hydrophobicity | 1.133 |
| Hydrophilicity | 1.091 |
| Buriedness | 0.868 |
| Don/acc character | 1.224 |
| SiteScore | 0.924 |
| D Score | 0.862 |
| Kd | — |
| Compound | GTP |
| Residue | . / 1666 |
| Chain | H / A |
| Non-redundant | False |
| Interacting RNA chains | B/B |
| RNA environment detailled | protein, ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | B/B: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 651.01 Å3 |
| Hydrophobicity | 1.073 |
| Hydrophilicity | 1.188 |
| Buriedness | 0.858 |
| Don/acc character | 0.599 |
| SiteScore | 1.107 |
| D Score | 1.068 |
| Kd | — |
| Compound | GTP |
| Residue | . / 1665 |
| Chain | L / C |
| Non-redundant | False |
| Interacting RNA chains | D/D |
| RNA environment detailled | protein, ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | D/D: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 272.00 Å3 |
| Hydrophobicity | 1.056 |
| Hydrophilicity | 1.089 |
| Buriedness | 0.863 |
| Don/acc character | 0.992 |
| SiteScore | 0.945 |
| D Score | 0.891 |
| Kd | — |
| Compound | GTP |
| Residue | . / 1666 |
| Chain | M / C |
| Non-redundant | False |
| Interacting RNA chains | D/D |
| RNA environment detailled | protein, ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | D/D: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 658.22 Å3 |
| Hydrophobicity | 1.030 |
| Hydrophilicity | 1.175 |
| Buriedness | 0.858 |
| Don/acc character | 0.677 |
| SiteScore | 1.107 |
| D Score | 1.071 |
| Kd | — |
| Compound | GTP |
| Residue | . / 1665 |
| Chain | Q / E |
| Non-redundant | False |
| Interacting RNA chains | F/F |
| RNA environment detailled | protein, ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | F/F: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 298.75 Å3 |
| Hydrophobicity | 0.918 |
| Hydrophilicity | 1.033 |
| Buriedness | 0.854 |
| Don/acc character | 0.895 |
| SiteScore | 0.916 |
| D Score | 0.873 |
| Kd | — |
| Compound | GTP |
| Residue | . / 1666 |
| Chain | R / E |
| Non-redundant | False |
| Interacting RNA chains | F/F |
| RNA environment detailled | protein, ion, other |
| RNA environment global | RNA/Other |
| RNA family chains | F/F: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 619.12 Å3 |
| Hydrophobicity | 1.147 |
| Hydrophilicity | 1.079 |
| Buriedness | 0.863 |
| Don/acc character | 0.548 |
| SiteScore | 1.110 |
| D Score | 1.106 |
| Kd | — |