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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 1ibk

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 3.31
System mass 788.83 kDa
Deposition year 2001
Molecule type RNA/Protein
# RNA entities 1
Organism Thermus
RCSB PDB Entry 1ibk
Reference Ogle James M., Brodersen Ditlev E., Clemons William M., Tarry Michael J., Carter Andrew P., Ramakrishnan V.. 2001. Recognition of Cognate Transfer RNA by the 30 S Ribosomal Subunit Science
Equivalence Class NR_all_65795.87
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound PAR
Residue . / 1545
Chain W / A
Non-redundant False
Interacting RNA chains A/A
RNA environment detailled ion
RNA environment global RNA
RNA family chains A/A: rRNA
RNA family global rRNA
Volume 93.64 Å3
Hydrophobicity 0.035
Hydrophilicity 0.940
Buriedness 0.568
Don/acc character 2.852
SiteScore 0.783
D Score 0.590
Kd