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HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9vxm

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 2.90
System mass 2953.06 kDa
Deposition year 2025
Molecule type RNA/Protein
# RNA entities 1
Organism Homo
RCSB PDB Entry 9vxm
Equivalence Class NR_all_12763.37, NR_all_93855.32
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound NAD
Residue . / 1701
Chain RJ / AA
Non-redundant True
Interacting RNA chains TA/AA
RNA environment detailled protein, ion
RNA environment global RNA/Protein
RNA family chains TA/AA: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound NMY
Residue . / 3470
Chain ZI / A
Non-redundant True
Interacting RNA chains K/A
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains K/A: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound NMY
Residue . / 3471
Chain AJ / A
Non-redundant True
Interacting RNA chains K/A
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains K/A: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound NMY
Residue . / 3473
Chain CJ / A
Non-redundant True
Interacting RNA chains K/A
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains K/A: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound NMY
Residue . / 3474
Chain DJ / A
Non-redundant True
Interacting RNA chains K/A
RNA environment detailled protein, ion
RNA environment global RNA/Protein
RNA family chains K/A: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound NMY
Residue . / 1783
Chain VM / AA
Non-redundant True
Interacting RNA chains TA/AA
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains TA/AA: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound NMY
Residue . / 1784
Chain WM / AA
Non-redundant True
Interacting RNA chains TA/AA
RNA environment detailled protein
RNA environment global RNA/Protein
RNA family chains TA/AA: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound NMY
Residue . / 1785
Chain XM / AA
Non-redundant True
Interacting RNA chains YB/Az, TA/AA
RNA environment detailled protein
RNA environment global RNA/Protein
RNA family chains TA/AA: rRNA, YB/Az: mRNA
RNA family global multiple
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound NMY
Residue . / 1786
Chain YM / AA
Non-redundant True
Interacting RNA chains TA/AA, K/A
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains K/A: rRNA, TA/AA: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd

Compound SPM
Residue . / 1702
Chain SJ / AA
Non-redundant True
Interacting RNA chains TA/AA
RNA environment detailled ion
RNA environment global RNA
RNA family chains TA/AA: rRNA
RNA family global rRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd