Complex 9nl3
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 3.20 |
| System mass | 277.01 kDa |
| Deposition year | 2025 |
| Molecule type | RNA/DNA/Protein |
| # RNA entities | 1 |
| Organism | N/A |
| RCSB PDB Entry | 9nl3 |
| Reference | Thawani Akanksha, Rodríguez-Vargas Anthony, Van Treeck Briana, Hassan Nozhat T., Adelson David L., Nogales Eva, Collins Kathleen. 2025. Structures of vertebrate R2 retrotransposon complexes during target-primed reverse transcription and after second-strand nicking Science Advances |
| Equivalence Class |
NR_all_79347.2
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | TTP |
| Residue | . / 1206 |
| Chain | K / A |
| Non-redundant | True |
| Interacting RNA chains | D/R |
| RNA environment detailled | DNA, protein, ion |
| RNA environment global | RNA/DNA/Protein |
| RNA family chains | D/R: synthetic construct |
| RNA family global | synthetic construct |
| Volume | 311.44 Å3 |
| Hydrophobicity | 0.340 |
| Hydrophilicity | 1.338 |
| Buriedness | 0.796 |
| Don/acc character | 0.425 |
| SiteScore | 1.016 |
| D Score | 0.918 |
| Kd | — |