HARIBOSS logo

HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9ja1

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 2.98
System mass 549.17 kDa
Deposition year 2024
Molecule type RNA/DNA/Protein
# RNA entities 1
Organism N/A
RCSB PDB Entry 9ja1
Reference Ma Jianbing, Yi Gangshun, Ye Mingda, MacGregor-Chatwin Craig, Sheng Yuewen, Lu Ying, Li Ming, Li Qingrong, Wang Dong, Gilbert Robert J. C., Zhang Peijun. 2024. Open architecture of archaea MCM and dsDNA complexes resolved using monodispersed streptavidin affinity CryoEM Nature Communications

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound ATP
Residue . / 101
Chain W / T
Non-redundant True
Interacting RNA chains L/R
RNA environment detailled DNA, protein
RNA environment global RNA/DNA/Protein
RNA family chains L/R: synthetic construct
RNA family global synthetic construct
Volume 748.08 Å3
Hydrophobicity 0.470
Hydrophilicity 1.266
Buriedness 0.853
Don/acc character 1.009
SiteScore 1.103
D Score 1.039
Kd