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Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9j4o

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique X-ray
Experimental resolution 2.50
System mass 28.95 kDa
Deposition year 2024
Molecule type RNA
# RNA entities 1
Organism Bacillus
RCSB PDB Entry 9j4o
Reference Cho Gyuhyeok, Yoo Jaehun, Shin Kiroo, Lee Jangmin, Lim Jihyo, Kim Jungwook. 2025. Crystal structures of free-state tRNALeu reveal conformational flexibility of type-II tRNAs RNA
Equivalence Class NR_all_36224.1
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound SPM
Residue . / 101
Chain B / A
Non-redundant True
Interacting RNA chains A/A
RNA environment detailled RNA-only
RNA environment global RNA
RNA family chains A/A: tRNA
RNA family global tRNA
Volume -
Hydrophobicity -
Hydrophilicity -
Buriedness -
Don/acc character -
SiteScore -
D Score -
Kd