HARIBOSS logo

HARIBOSS

Harnessing RIBOnucleic acid - Small molecules Structures

Illustration - complex

Complex 9c0j

Legend

Pocket colors by molecule type

 RNA

 Protein

 DNA

These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).

System information

Experimental technique Electron Microscopy
Experimental resolution 3.17
System mass 144.03 kDa
Deposition year 2024
Molecule type RNA/DNA/Protein
# RNA entities 1
Organism Klebsiella
RCSB PDB Entry 9c0j
Reference Wilkinson Max E., Li David, Gao Alex, Macrae Rhiannon K., Zhang Feng. 2024. Phage-triggered reverse transcription assembles a toxic repetitive gene from a noncoding RNA Science
Equivalence Class NR_all_52922.1
BGSU version: 4.52

Pockets List

Legend

Cell colors for SiteScore and D Score:

 Favourable

 Intermediate

 Unfavourable

 Not available

ScoreThresholdMeaning
SiteScore< 0.8Non-drug binding site
SiteScore0.8 – 1.0Potential drug binding site
SiteScore> 1.0Promising binding site
D Score< 0.83Undruggable
D Score0.83 – 0.98Difficult
D Score> 0.98Druggable

Tick a pocket below to highlight it in the 3D structure above.

Compound TTP
Residue . / 502
Chain E / A
Non-redundant True
Interacting RNA chains C/R
RNA environment detailled DNA, protein, ion
RNA environment global RNA/DNA/Protein
RNA family chains C/R: unknown
RNA family global unknown
Volume 336.48 Å3
Hydrophobicity 0.807
Hydrophilicity 1.108
Buriedness 0.782
Don/acc character 0.798
SiteScore 1.056
D Score 1.048
Kd