Complex 8i7n
Legend
Pocket colors by molecule type
RNA
Protein
DNA
These colors appear when a pocket is selected (the structure fades to show the pocket surface). Colors from the molecule-type palette (RNA / protein / DNA).
System information
| Experimental technique | Electron Microscopy |
| Experimental resolution | 2.98 |
| System mass | 135.88 kDa |
| Deposition year | 2023 |
| Molecule type | RNA |
| # RNA entities | 1 |
| Organism | Tetrahymena |
| RCSB PDB Entry | 8i7n |
| Reference | Luo Bingnan, Zhang Chong, Ling Xiaobin, Mukherjee Sunandan, Jia Guowen, Xie Jiahao, Jia Xinyu, Liu Liu, Baulin Eugene F., Luo Yongbo, Jiang Longxing, Dong Haohao, Wei Xiawei, Bujnicki Janusz M., Su Zhaoming. 2023. Cryo-EM reveals dynamics of Tetrahymena group I intron self-splicing Nature Catalysis |
| Equivalence Class |
NR_all_69141.8
BGSU version: 4.52 |
Pockets List
Legend
Cell colors for SiteScore and D Score:
Favourable
Intermediate
Unfavourable
Not available
| Score | Threshold | Meaning |
|---|---|---|
| SiteScore | < 0.8 | Non-drug binding site |
| SiteScore | 0.8 – 1.0 | Potential drug binding site |
| SiteScore | > 1.0 | Promising binding site |
| D Score | < 0.83 | Undruggable |
| D Score | 0.83 – 0.98 | Difficult |
| D Score | > 0.98 | Druggable |
Tick a pocket below to highlight it in the 3D structure above.
| Compound | OJI |
| Residue | . / 529 |
| Chain | DA / N |
| Non-redundant | True |
| Interacting RNA chains | A/N |
| RNA environment detailled | ion |
| RNA environment global | RNA |
| RNA family chains | A/N: ribozyme |
| RNA family global | ribozyme |
| Volume | 507.30 Å3 |
| Hydrophobicity | 0.195 |
| Hydrophilicity | 1.192 |
| Buriedness | 0.747 |
| Don/acc character | 3.148 |
| SiteScore | 1.183 |
| D Score | 1.000 |
| Kd | — |